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Psmb7 Gene Detail
Summary
  • Symbol
    Psmb7
  • Name
    proteasome (prosome, macropain) subunit, beta type 7
  • Synonyms
    MC14
  • Feature Type
    protein coding gene
  • IDs
    MGI:107637
    NCBI Gene: 19177
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:38478058-38533964 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 24.42 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1202 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107637
 protein coding gene Chr2:38478048-38534099 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025703
 protein coding gene Chr2:37346454-37408364 (-)
A/J MGP_AJ_G0025680
 protein coding gene Chr2:35811461-35869243 (-)
AKR/J MGP_AKRJ_G0025650
 protein coding gene Chr2:36992940-37054415 (-)
BALB/cJ MGP_BALBcJ_G0025675
 protein coding gene Chr2:35865025-35920604 (-)
C3H/HeJ MGP_C3HHeJ_G0025436
 protein coding gene Chr2:36908528-36966888 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026121
 protein coding gene Chr2:38385815-38441538 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023526
 protein coding gene Chr2:34466477-34525555 (-)
CAST/EiJ MGP_CASTEiJ_G0024899
 protein coding gene Chr2:36857640-36917634 (-)
CBA/J MGP_CBAJ_G0025415
 protein coding gene Chr2:39817848-39878992 (-)
DBA/2J MGP_DBA2J_G0025547
 protein coding gene Chr2:35558881-35617328 (-)
FVB/NJ MGP_FVBNJ_G0025509
 protein coding gene Chr2:35425371-35484332 (-)
LP/J MGP_LPJ_G0025634
 protein coding gene Chr2:37226023-37288162 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025540
 protein coding gene Chr2:39425387-39488064 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026179
 protein coding gene Chr2:36883514-36941272 (-)
PWK/PhJ MGP_PWKPhJ_G0024641
 protein coding gene Chr2:35460468-35519632 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024446
 protein coding gene Chr2:36994204-37054923 (-)
WSB/EiJ MGP_WSBEiJ_G0024967
 protein coding gene Chr2:37053833-37115978 (-)



Homology
more
  • Human Ortholog
    PSMB7, proteasome 20S subunit beta 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMB7, proteasome 20S subunit beta 7
  • Links
    NCBI Gene ID: 5695
    neXtProt AC: NX_Q99436
    UniProt: Q99436

  • Chr Location
    9q33.3; chr9:124353465-124415444 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    1
  • cDNA Data
    222
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19177 NCBI Gene Model | MGI Sequence Detail 55907 C57BL/6J ±  kb
transcript NM_011187 RefSeq | MGI Sequence Detail 969 C57BL/6  
polypeptide P70195 UniProt | EBI | MGI Sequence Detail 277 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 224
    Genomic 1
    cDNA 222
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36211
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:35593 Kasahara M, et al., Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex. Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9096-101
  • Latest
    J:266104 Choi JH, et al., mTORC1 accelerates retinal development via the immunoproteasome. Nat Commun. 2018 Jun 27;9(1):2502
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory