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Exosc5 Gene Detail
Summary
  • Symbol
    Exosc5
  • Name
    exosome component 5
  • Synonyms
    D7Wsu180e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107889
    NCBI Gene: 27998
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:25358578-25367457 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 13.96 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    298 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107889
 protein coding gene Chr7:25358578-25370793 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031873
 protein coding gene Chr7:24165801-24177992 (+)
A/J MGP_AJ_G0031852
 protein coding gene Chr7:23530419-23542617 (+)
AKR/J MGP_AKRJ_G0031781
 protein coding gene Chr7:24132773-24145933 (+)
BALB/cJ MGP_BALBcJ_G0031857
 protein coding gene Chr7:23772725-23784921 (+)
C3H/HeJ MGP_C3HHeJ_G0031578
 protein coding gene Chr7:24548762-24561193 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032321
 protein coding gene Chr7:24978794-24990985 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029376
 protein coding gene Chr7:24873128-24885470 (+)
CAST/EiJ MGP_CASTEiJ_G0030918
 protein coding gene Chr7:17960914-17973225 (+)
CBA/J MGP_CBAJ_G0031543
 protein coding gene Chr7:25855785-25867986 (+)
DBA/2J MGP_DBA2J_G0031697
 protein coding gene Chr7:23428164-23440358 (+)
FVB/NJ MGP_FVBNJ_G0031650
 protein coding gene Chr7:23459003-23471695 (+)
LP/J MGP_LPJ_G0031776
 protein coding gene Chr7:24444812-24457012 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031687
 protein coding gene Chr7:25589269-25601448 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032353
 protein coding gene Chr7:23777308-23790915 (+)
PWK/PhJ MGP_PWKPhJ_G0030642
 protein coding gene Chr7:18378344-18390684 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030472
 protein coding gene Chr7:15099689-15113558 (+)
WSB/EiJ MGP_WSBEiJ_G0031021
 protein coding gene Chr7:23997744-24009920 (+)



Homology
more
  • Human Ortholog
    EXOSC5, exosome component 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EXOSC5, exosome component 5
  • Synonyms
    CABAC, hRrp46p, p12B, RRP41B, RRP46, Rrp46p
  • Links
    NCBI Gene ID: 56915
    neXtProt AC: NX_Q9NQT4
    UniProt: Q9NQT4

  • Chr Location
    19q13.2; chr19:41386371-41397362 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    18
  • cDNA Data
    13
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27998 NCBI Gene Model | MGI Sequence Detail 8880 C57BL/6J ±  kb
transcript NR_104358 RefSeq | MGI Sequence Detail 1118 ZRU/MplStud  
polypeptide Q9CRA8 UniProt | EBI | MGI Sequence Detail 235 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36466
References
more
  • Summaries
    All 43
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:47941 Jaradat SA, et al., Tissue-specific expression and mapping of the Cox7ah gene in mouse (Erratum: 1998;54(3):583-4). Genomics. 1998 May 1;49(3):363-70
  • Latest
    J:343201 Srinivasan S, et al., Exosome complex components 1 and 2 are vital for early mammalian development. Gene Expr Patterns. 2024 March;51:119346
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory