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Selenoi Gene Detail
Summary
  • Symbol
    Selenoi
  • Name
    selenoprotein I
  • Synonyms
    4933402G07Rik, C79563, D5Wsu178e, Ept1, mKIAA1724
  • Feature Type
    protein coding gene
  • IDs
    MGI:107898
    NCBI Gene: 28042
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:30437579-30477425 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 16.22 cM, cytoband B1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    951 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107898
 protein coding gene Chr5:30437579-30477428 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029387
 protein coding gene Chr5:28208770-28248531 (+)
A/J MGP_AJ_G0029353
 protein coding gene Chr5:27286542-27326781 (+)
AKR/J MGP_AKRJ_G0029304
 protein coding gene Chr5:28363511-28403305 (+)
BALB/cJ MGP_BALBcJ_G0029364
 protein coding gene Chr5:27814654-27854458 (+)
C3H/HeJ MGP_C3HHeJ_G0029085
 protein coding gene Chr5:28416440-28456268 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029817
 protein coding gene Chr5:29937250-29978167 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027055
 protein coding gene Chr5:24788618-24825860 (+)
CAST/EiJ MGP_CASTEiJ_G0028496
 protein coding gene Chr5:27500669-27541482 (+)
CBA/J MGP_CBAJ_G0029053
 protein coding gene Chr5:30510372-30550229 (+)
DBA/2J MGP_DBA2J_G0029202
 protein coding gene Chr5:27479277-27519305 (+)
FVB/NJ MGP_FVBNJ_G0029160
 protein coding gene Chr5:26884647-26924474 (+)
LP/J MGP_LPJ_G0029287
 protein coding gene Chr5:28659010-28698811 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029189
 protein coding gene Chr5:31435311-31475065 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029851
 protein coding gene Chr5:27927295-27967835 (+)
PWK/PhJ MGP_PWKPhJ_G0028220
 protein coding gene Chr5:26586651-26627680 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028051
 protein coding gene Chr5:27267976-27308526 (+)
WSB/EiJ MGP_WSBEiJ_G0028576
 protein coding gene Chr5:28004981-28045023 (+)



Homology
more
  • Human Ortholog
    SELENOI, selenoprotein I
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SELENOI, selenoprotein I
  • Synonyms
    EPT1, SELI, SEPI, SPG81
  • Links
    NCBI Gene ID: 85465
    neXtProt AC: NX_Q9C0D9
    UniProt: Q9C0D9

  • Chr Location
    2p23.3; chr2:26308547-26395885 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SELENOI associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    29 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit early-stage embryonic lethality prior to E6.5, with a rare survival to the perinatal stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    804
  • Tissues
    98
  • cDNA Data
    29
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075703 Ensembl Gene Model | MGI Sequence Detail 39847 C57BL/6J ±  kb
transcript ENSMUST00000145167 Ensembl | MGI Sequence Detail 6803 Not Applicable  
polypeptide ENSMUSP00000118368 Ensembl | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000014608 ethanolaminephosphotransferase 1
    (term hierarchy)
  • EC
    2.7.8.1
  • InterPro Domains
    IPR000462 CDP-alcohol phosphatidyltransferase
    IPR048254 CDP-alcohol phosphatidyltransferase, conserved site
    IPR043130 CDP-alcohol phosphatidyltransferase, transmembrane domain
    IPR014472 Choline/ethanolamine phosphotransferase
  • GlyGen
    Q80TA1 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 33
    cDNA 30
    Primer pair 3

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-36477, MGI:1918278, MGI:2140883, MGI:2140900, MGI:2141310
References
more
  • Summaries
    All 65
    Developmental Gene Expression 2
    Diseases 1
    Gene Ontology 7
    Phenotypes 29
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:349396 Nunes LGA, et al., Selenoprotein I is indispensable for ether lipid homeostasis and proper myelination. J Biol Chem. 2024 Apr 4;300(5):107259
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory