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Nfyc Gene Detail
Summary
  • Symbol
    Nfyc
  • Name
    nuclear transcription factor-Y gamma
  • Feature Type
    protein coding gene
  • IDs
    MGI:107901
    NCBI Gene: 18046
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:120614635-120688769 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.52 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1177 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107901
 protein coding gene Chr4:120614632-120688776 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028714
 protein coding gene Chr4:122037206-122121379 (-)
A/J MGP_AJ_G0028674
 protein coding gene Chr4:117234500-117310621 (-)
AKR/J MGP_AKRJ_G0028627
 protein coding gene Chr4:119803950-119896584 (-)
BALB/cJ MGP_BALBcJ_G0028697
 protein coding gene Chr4:117844053-117921219 (-)
C3H/HeJ MGP_C3HHeJ_G0028412
 protein coding gene Chr4:121339641-121411696 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029138
 protein coding gene Chr4:126637777-126723616 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026415
 protein coding gene Chr4:111289122-111357351 (-)
CAST/EiJ MGP_CASTEiJ_G0027843
 protein coding gene Chr4:118710220-118790286 (-)
CBA/J MGP_CBAJ_G0028379
 protein coding gene Chr4:130077031-130155074 (-)
DBA/2J MGP_DBA2J_G0028526
 protein coding gene Chr4:117809922-117887527 (-)
FVB/NJ MGP_FVBNJ_G0028492
 protein coding gene Chr4:116334210-116409178 (-)
LP/J MGP_LPJ_G0028626
 protein coding gene Chr4:122168544-122250408 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028520
 protein coding gene Chr4:134899645-134987221 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029175
 protein coding gene Chr4:120874740-120957414 (-)
PWK/PhJ MGP_PWKPhJ_G0027566
 protein coding gene Chr4:114752680-114822029 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027392
 protein coding gene Chr4:117312555-117381222 (-)
WSB/EiJ MGP_WSBEiJ_G0027923
 protein coding gene Chr4:120893385-120982083 (-)



Homology
more
  • Human Ortholog
    NFYC, nuclear transcription factor Y subunit gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NFYC, nuclear transcription factor Y subunit gamma
  • Synonyms
    CBF-C, CBFC, H1TF2A, HAP5, HSM, NF-YC
  • Links
    NCBI Gene ID: 4802
    neXtProt AC: NX_Q13952
    UniProt: Q13952

  • Chr Location
    1p34.2; chr1:40691648-40771603 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    773
  • Tissues
    63
  • cDNA Data
    12
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032897 Ensembl Gene Model | MGI Sequence Detail 74135 C57BL/6J ±  kb
transcript ENSMUST00000043429 Ensembl | MGI Sequence Detail 1932 Not Applicable  
polypeptide ENSMUSP00000047441 Ensembl | MGI Sequence Detail 335 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 13
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36480
References
more
  • Summaries
    All 57
    Developmental Gene Expression 8
    Gene Ontology 10
    Phenotypes 15
  • Earliest
    J:36015 Sinha S, et al., Chromosomal assignment and tissue expression of CBF-C/NFY-C, the third subunit of the mammalian CCAAT-binding factor. Genomics. 1996 Oct 15;37(2):260-3
  • Latest
    J:345074 Yamanaka T, et al., The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory