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Ptprv Pseudogene Detail
Summary
  • Symbol
    Ptprv
  • Name
    protein tyrosine phosphatase receptor type V
  • Synonyms
    Esp, mOST-PTP, OST, OST-PTP
Location &
Maps
more
  • Sequence Map
    Chr1:135036236-135060313 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 58.24 cM, cytoband F-G
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    639 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108027
 polymorphic pseudogene Chr1:135036235-135060332 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015112
 unclassified non-coding RNA gene Chr1:138844012-138869360 (-)
A/J MGP_AJ_G0015085
 unclassified non-coding RNA gene Chr1:133598434-133625587 (-)
AKR/J MGP_AKRJ_G0015048
 unclassified non-coding RNA gene Chr1:137579074-137602891 (-)
BALB/cJ MGP_BALBcJ_G0015048
 unclassified non-coding RNA gene Chr1:133914434-133939299 (-)
C3H/HeJ MGP_C3HHeJ_G0014871
 unclassified non-coding RNA gene Chr1:137672546-137696403 (-)
C57BL/6NJ MGP_C57BL6NJ_G0015505
 unclassified non-coding RNA gene Chr1:143868710-143895272 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013251
 unclassified non-coding RNA gene Chr1:126712954-126736776 (-)
CAST/EiJ MGP_CASTEiJ_G0014426
 unclassified non-coding RNA gene Chr1:136745272-136769916 (-)
CBA/J MGP_CBAJ_G0014850
 unclassified non-coding RNA gene Chr1:148828564-148852378 (-)
DBA/2J MGP_DBA2J_G0014943
 unclassified non-coding RNA gene Chr1:132602672-132626813 (-)
FVB/NJ MGP_FVBNJ_G0014955
 unclassified non-coding RNA gene Chr1:131238371-131263662 (-)
LP/J MGP_LPJ_G0015026
 unclassified non-coding RNA gene Chr1:140087242-140112867 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0014982
 unclassified non-coding RNA gene Chr1:154528720-154555500 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0015543
 unclassified non-coding RNA gene Chr1:137322255-137347647 (-)
PWK/PhJ MGP_PWKPhJ_G0014218
 unclassified non-coding RNA gene Chr1:131624953-131650084 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014007
 unclassified non-coding RNA gene Chr1:136285408-136311263 (-)
WSB/EiJ MGP_WSBEiJ_G0014529
 unclassified non-coding RNA gene Chr1:137350858-137378475 (-)



Homology
more
  • Human Ortholog
    PTPRVP, protein tyrosine phosphatase receptor type V, pseudogene
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTPRVP, protein tyrosine phosphatase receptor type V, pseudogene
  • Synonyms
    ESP, OST-PTP, PTPRV
  • Links
    NCBI Gene ID: 148713

  • Chr Location
    1q32.1; chr1:202168051-202189455 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    46 phenotypes from 4 alleles in 7 genetic backgrounds
    6 phenotypes from multigenic genotypes
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased resistance to diet-induced obesity, decreased circulating glucose levels, and decreased suseptibility to death induced by streptozotocin treatment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    951
  • Tissues
    93
  • cDNA Data
    11
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      44
    • RefSeq
      3
    • UniProt
      4
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13924 NCBI Gene Model | MGI Sequence Detail 24078 C57BL/6J ±  kb
    transcript NR_153383 RefSeq | MGI Sequence Detail 6089 C57BL/6  
    polypeptide P70289 UniProt | EBI | MGI Sequence Detail 1705 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000013560 receptor-type tyrosine-protein phosphatase V
      (term hierarchy)
    • EC
      3.1.3.48
    • InterPro Domains
      IPR003961 Fibronectin type III
      IPR036116 Fibronectin type III superfamily
      IPR013783 Immunoglobulin-like fold
      IPR016130 Protein-tyrosine phosphatase, active site
      IPR003595 Protein-tyrosine phosphatase, catalytic
      IPR029021 Protein-tyrosine phosphatase-like
      IPR041201 PTPRJ, transmembrane domain
      IPR050713 Receptor-type Tyrosine-protein Phosphatases/Ushers
      IPR000242 Tyrosine-specific protein phosphatase, PTPase domain
      IPR000387 Tyrosine-specific protein phosphatases domain
    • GlyGen
      P70289 19 sites, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 12
      Primer pair 3
      Other 5

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-37063, MGI:1927839
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 8
      Gene Ontology 8
      Phenotypes 20
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    11/12/2024
    MGI 6.24     		The Jackson Laboratory