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Zik1 Gene Detail
Summary
  • Symbol
    Zik1
  • Name
    zinc finger protein interacting with K protein 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:108070
    NCBI Gene: 22775
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:10221151-10229308 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 6.47 cM, cytoband A1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    193 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108070
 protein coding gene Chr7:10221151-10229321 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031623
 protein coding gene Chr7:7743892-7752057 (-)
A/J MGP_AJ_G0031599
 protein coding gene Chr7:7581633-7589798 (-)
AKR/J MGP_AKRJ_G0031525
 protein coding gene Chr7:7847633-7855799 (-)
BALB/cJ MGP_BALBcJ_G0031606
 protein coding gene Chr7:7719746-7727911 (-)
C3H/HeJ MGP_C3HHeJ_G0031327
 protein coding gene Chr7:7739133-7747298 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032070
 protein coding gene Chr7:8174667-8182832 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030687
 protein coding gene Chr7:5741240-5749408 (-)
CBA/J MGP_CBAJ_G0031284
 protein coding gene Chr7:8279298-8287463 (-)
DBA/2J MGP_DBA2J_G0031442
 protein coding gene Chr7:7498595-7506760 (-)
FVB/NJ MGP_FVBNJ_G0031396
 protein coding gene Chr7:7505212-7513368 (-)
LP/J MGP_LPJ_G0031528
 protein coding gene Chr7:7802059-7810224 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031435
 protein coding gene Chr7:8297707-8305872 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032098
 protein coding gene Chr7:7586174-7594339 (-)
PWK/PhJ MGP_PWKPhJ_G0030414
 protein coding gene Chr7:6118040-6126205 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030242
 protein coding gene Chr7:4432038-4439976 (-)
WSB/EiJ MGP_WSBEiJ_G0030782
 protein coding gene Chr7:7708970-7717135 (-)



Homology
more
  • Human Ortholog
    ZIK1, zinc finger protein interacting with K protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZIK1, zinc finger protein interacting with K protein 1
  • Synonyms
    ZNF762
  • Links
    NCBI Gene ID: 284307
    neXtProt AC: NX_Q3SY52
    UniProt: Q3SY52

  • Chr Location
    19q13.43; chr19:57578456-57593890 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    833
  • Tissues
    66
  • cDNA Data
    46
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22775 NCBI Gene Model | MGI Sequence Detail 8158 C57BL/6J ±  kb
transcript NM_009577 RefSeq | MGI Sequence Detail 4191 C57BL/6  
polypeptide Q80YP6 UniProt | EBI | MGI Sequence Detail 463 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 47
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-37107
References
more
  • Summaries
    All 33
    Developmental Gene Expression 10
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:36496 Denisenko ON, et al., Zik1, a transcriptional repressor that interacts with the heterogeneous nuclear ribonucleoprotein particle K protein. J Biol Chem. 1996 Nov 1;271(44):27701-6
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory