Zfp92 MGI Mouse Gene Detail - MGI:108094

Symbol

Zfp92
Name

zinc finger protein 92

Feature Type

protein coding gene
IDs

MGI:108094
NCBI Gene: 22754
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

ChrX:72454702-72471991 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome X, 37.31 cM
Mapping Data

1 experiment

SNPs within 2kb

461 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_108094	protein coding gene	ChrX:72454555-72473980 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0035808	protein coding gene	ChrX:69156359-69175875 (+)
A/J	MGP_AJ_G0035789	protein coding gene	ChrX:69371055-69391222 (+)
AKR/J	MGP_AKRJ_G0035714	protein coding gene	ChrX:71181182-71200826 (+)
BALB/cJ	MGP_BALBcJ_G0035774	protein coding gene	ChrX:68409008-68426277 (+)
C3H/HeJ	MGP_C3HHeJ_G0035479	protein coding gene	ChrX:69637919-69656218 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0036304	protein coding gene	ChrX:71294723-71314610 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0033148	protein coding gene	ChrX:68420895-68438052 (+)
CAST/EiJ	MGP_CASTEiJ_G0034770	protein coding gene	ChrX:54989324-55006531 (+)
CBA/J	MGP_CBAJ_G0035454	protein coding gene	ChrX:73236252-73253437 (+)
DBA/2J	MGP_DBA2J_G0035611	protein coding gene	ChrX:68840848-68859014 (+)
FVB/NJ	MGP_FVBNJ_G0035555	protein coding gene	ChrX:68166943-68185189 (+)
LP/J	MGP_LPJ_G0035696	protein coding gene	ChrX:69966183-69983473 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035593	protein coding gene	ChrX:75831036-75849955 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0036326	protein coding gene	ChrX:68986850-69005178 (+)
PWK/PhJ	MGP_PWKPhJ_G0034469	protein coding gene	ChrX:53009786-53026894 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0034303	protein coding gene	ChrX:55907988-55925257 (+)
WSB/EiJ	MGP_WSBEiJ_G0034911	protein coding gene	ChrX:68263893-68282756 (+)

Human Ortholog

ZFP92, ZFP92 zinc finger protein

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZFP92, ZFP92 zinc finger protein
Synonyms

ZNF897
Links

HGNC:12865

NCBI Gene ID: 139735

neXtProt AC: NX_A6NM28

UniProt: A6NM28
Chr Location

Xq28; chrX:153411472-153426481 (+) GRCh38

MGI Vertebrate Homology

Zfp92 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: ZFP92
Gene Tree

Zfp92

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Phenotype Summary

5 phenotypes from 2 alleles in 2 genetic backgrounds
8 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Endonuclease-mediated

3
Targeted

1
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

13 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a null allele exhibit normal postnatal survival.

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All GO Annotations

8
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

771
Tissues

45
cDNA Data

7
Literature Summary

6

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

42
RefSeq

10
UniProt

2
CCDS

CCDS30200.1, CCDS81135.1

Ensembl

ENSMUSG00000031374 (Evidence)
NCBI Gene

22754

			Length	Strain/Species	Flank
genomic	ENSMUSG00000031374	Ensembl Gene Model \| MGI Sequence Detail	17290	C57BL/6J	± kb
transcript	ENSMUST00000033740	Ensembl \| MGI Sequence Detail	5767	Not Applicable
polypeptide	ENSMUSP00000033740	Ensembl \| MGI Sequence Detail	488	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000017650 zinc finger protein 92 homolog

(term hierarchy)
InterPro Domains

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

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All nucleic 14

Genomic 1

cDNA 10

Primer pair 3

Microarray probesets 3

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MGD-MRK-37131

Summaries

All 32

Developmental Gene Expression 6

Gene Ontology 4

Phenotypes 8
Earliest

J:33576 Levin ML, et al., A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp92:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr161203	ChrX:72454703-72454731 (+)	15 bp
Tssr161204	ChrX:72464312-72464314 (+)	9,611 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24