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Ddn Gene Detail
Summary
  • Symbol
    Ddn
  • Name
    dendrin
  • Synonyms
    LOC328602
  • Feature Type
    protein coding gene
  • IDs
    MGI:108101
    NCBI Gene: 13199
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:98701663-98705806 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 54.69 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    91 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108101
 protein coding gene Chr15:98701658-98707371 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022312
 protein coding gene Chr15:100564639-100568821 (-)
A/J MGP_AJ_G0022270
 protein coding gene Chr15:96592251-96596393 (-)
AKR/J MGP_AKRJ_G0022245
 protein coding gene Chr15:99565055-99569197 (-)
BALB/cJ MGP_BALBcJ_G0022277
 protein coding gene Chr15:96785202-96791220 (-)
C3H/HeJ MGP_C3HHeJ_G0022045
 protein coding gene Chr15:99617661-99623001 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022722
 protein coding gene Chr15:104306575-104311682 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020247
 protein coding gene Chr15:92509133-92513262 (-)
CAST/EiJ MGP_CASTEiJ_G0021568
 protein coding gene Chr15:100466708-100470774 (-)
CBA/J MGP_CBAJ_G0022014
 protein coding gene Chr15:107845365-107853373 (-)
DBA/2J MGP_DBA2J_G0022140
 protein coding gene Chr15:96036232-96040618 (-)
FVB/NJ MGP_FVBNJ_G0022120
 protein coding gene Chr15:95015611-95019990 (-)
LP/J MGP_LPJ_G0022212
 protein coding gene Chr15:100715511-100719650 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022140
 protein coding gene Chr15:111845044-111850461 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022737
 protein coding gene Chr15:99645539-99649727 (-)
PWK/PhJ MGP_PWKPhJ_G0021309
 protein coding gene Chr15:96158459-96162943 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021144
 protein coding gene Chr15:99498747-99502959 (-)
WSB/EiJ MGP_WSBEiJ_G0021618
 protein coding gene Chr15:100196269-100201104 (-)



Homology
more
  • Human Ortholog
    DDN, dendrin
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DDN, dendrin
  • Links
    NCBI Gene ID: 23109
    neXtProt AC: NX_O94850
    UniProt: O94850

  • Chr Location
    12q13.12; chr12:48995149-48999375 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    25 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    3 involving Ddn
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    16 strains or lines available
Mice homozygous for a knock-out allele exhibit normal proteinuria in resposne to LPS treatment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    8
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 13199 NCBI Gene Model | MGI Sequence Detail 4144 C57BL/6J ±  kb
transcript NM_001013741 RefSeq | MGI Sequence Detail 3740 ZRU/MplStud  
polypeptide Q80TS7 UniProt | EBI | MGI Sequence Detail 710 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGD-MRK-37138, MGI:2685594
References
more
  • Summaries
    All 49
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory