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Slbp Gene Detail
Summary
  • Symbol
    Slbp
  • Name
    stem-loop binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:108402
    NCBI Gene: 20492
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:33797399-33809918 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 17.83 cM, cytoband B1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    393 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108402
 protein coding gene Chr5:33792296-33809918 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029449
 protein coding gene Chr5:31818601-31840668 (-)
A/J MGP_AJ_G0029416
 protein coding gene Chr5:30786980-30805517 (-)
AKR/J MGP_AKRJ_G0029365
 protein coding gene Chr5:31974163-31993152 (-)
BALB/cJ MGP_BALBcJ_G0029426
 protein coding gene Chr5:31316594-31335451 (-)
C3H/HeJ MGP_C3HHeJ_G0029148
 protein coding gene Chr5:32013416-32033582 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029880
 protein coding gene Chr5:33702511-33727463 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027117
 protein coding gene Chr5:28588356-28605768 (-)
CAST/EiJ MGP_CASTEiJ_G0028557
 protein coding gene Chr5:31092079-31112196 (-)
CBA/J MGP_CBAJ_G0029116
 protein coding gene Chr5:34419482-34441905 (-)
DBA/2J MGP_DBA2J_G0029264
 protein coding gene Chr5:30965478-30984103 (-)
FVB/NJ MGP_FVBNJ_G0029223
 protein coding gene Chr5:30391392-30409462 (-)
LP/J MGP_LPJ_G0029349
 protein coding gene Chr5:32243064-32264965 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029253
 protein coding gene Chr5:35273017-35294542 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029913
 protein coding gene Chr5:31487347-31506683 (-)
PWK/PhJ MGP_PWKPhJ_G0028282
 protein coding gene Chr5:30099500-30117591 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028113
 protein coding gene Chr5:30942820-30959870 (-)
WSB/EiJ MGP_WSBEiJ_G0028638
 protein coding gene Chr5:31550170-31569106 (-)



Homology
more
  • Human Ortholog
    SLBP, stem-loop histone mRNA binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLBP, stem-loop histone mRNA binding protein
  • Synonyms
    HBP
  • Links
    NCBI Gene ID: 7884
    neXtProt AC: NX_Q14493
    UniProt: Q14493

  • Chr Location
    4p16.3; chr4:1692731-1712344 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1027
  • Tissues
    34
  • cDNA Data
    135
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 20492 NCBI Gene Model | MGI Sequence Detail 12520 C57BL/6J ±  kb
    transcript NM_009193 RefSeq | MGI Sequence Detail 1921 C57BL/6  
    polypeptide P97440 UniProt | EBI | MGI Sequence Detail 275 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • Protein Ontology
      PR:000014916 histone RNA hairpin-binding protein
      (term hierarchy)
    • InterPro Domains
      IPR029344 Histone RNA hairpin-binding protein, RNA-binding domain
      IPR026502 Histone RNA stem-loop-binding protein SLBP1/SLBP2
      IPR038294 SLBP, RNA-binding domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 138
      cDNA 136
      Primer pair 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-37444
    References
    more
    • Summaries
      All 63
      Developmental Gene Expression 7
      Diseases 1
      Gene Ontology 9
      Phenotypes 28
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    11/12/2024
    MGI 6.24     		The Jackson Laboratory