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Kifc3 Gene Detail
Summary
  • Symbol
    Kifc3
  • Name
    kinesin family member C3
  • Feature Type
    protein coding gene
  • IDs
    MGI:109202
    NCBI Gene: 16582
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:95826456-95929440 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 47.12 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2663 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109202
 protein coding gene Chr8:95826456-95929454 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033980
 protein coding gene Chr8:96557258-96593786 (-)
A/J MGP_AJ_G0033963
 protein coding gene Chr8:92796019-92832287 (-)
AKR/J MGP_AKRJ_G0033889
 protein coding gene Chr8:95319886-95356141 (-)
BALB/cJ MGP_BALBcJ_G0033955
 protein coding gene Chr8:92872666-92909475 (-)
C3H/HeJ MGP_C3HHeJ_G0033665
 protein coding gene Chr8:96039489-96075756 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034476
 protein coding gene Chr8:100067761-100104270 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031417
 protein coding gene Chr8:86593239-86629856 (-)
CAST/EiJ MGP_CASTEiJ_G0032997
 protein coding gene Chr8:95641197-95677481 (-)
CBA/J MGP_CBAJ_G0033641
 protein coding gene Chr8:103388166-103424448 (-)
DBA/2J MGP_DBA2J_G0033795
 protein coding gene Chr8:92279083-92316870 (-)
FVB/NJ MGP_FVBNJ_G0033742
 protein coding gene Chr8:91225392-91262593 (-)
LP/J MGP_LPJ_G0033887
 protein coding gene Chr8:96701172-96737426 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033784
 protein coding gene Chr8:105654464-105690691 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034494
 protein coding gene Chr8:95485128-95521992 (-)
PWK/PhJ MGP_PWKPhJ_G0032699
 protein coding gene Chr8:91642577-91679420 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032536
 protein coding gene Chr8:94338644-94374898 (-)
WSB/EiJ MGP_WSBEiJ_G0033109
 protein coding gene Chr8:96023257-96061845 (-)



Homology
more
  • Human Ortholog
    KIFC3, kinesin family member C3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIFC3, kinesin family member C3
  • Links
    NCBI Gene ID: 3801
    neXtProt AC: NX_Q9BVG8
    UniProt: Q9BVG8

  • Chr Location
    16q21; chr16:57758217-57863053 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for this targeted mutation are viable, fertile, and appear phenotypically indistinguishable from wild-type littermates.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    776
  • Tissues
    37
  • cDNA Data
    76
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000031788 Ensembl Gene Model | MGI Sequence Detail 102985 C57BL/6J ±  kb
    transcript ENSMUST00000034240 Ensembl | MGI Sequence Detail 3277 Not Applicable  
    polypeptide ENSMUSP00000034240 Ensembl | MGI Sequence Detail 824 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 78
      cDNA 76
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-38246, MGI:2142509, MGI:2142831
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 8
      Phenotypes 12
    • Earliest
      J:42822 Nakagawa T, et al., Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome. Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9654-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory