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Ctr9 Gene Detail
Summary
  • Symbol
    Ctr9
  • Name
    CTR9 homolog, Paf1/RNA polymerase II complex component
  • Synonyms
    Sh2bp1, Tsbp, Tsp
  • Feature Type
    protein coding gene
  • IDs
    MGI:109345
    NCBI Gene: 22083
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:110628158-110655584 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 57.98 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    599 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109345
 protein coding gene Chr7:110628158-110655584 (+)
129S1/SvImJ ENSMUSG00200033066
 protein coding gene Chr7:97171256-97198682 (+)
A/J ENSMUSG00195038029
 protein coding gene Chr7:101674696-101702121 (+)
AKR/J ENSMUSG00220033864
 protein coding gene Chr7:95077649-95105070 (+)
BALB/cJ ENSMUSG00180039446
 protein coding gene Chr7:98342826-98370249 (+)
C3H/HeJ ENSMUSG00175043611
 protein coding gene Chr7:98978694-99006117 (+)
C57BL/6NJ ENSMUSG00215049771
 protein coding gene Chr7:98283513-98310925 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030329
 protein coding gene Chr7:113309646-113340600 (+)
CAST/EiJ ENSTCUG00005043674
 protein coding gene Chr7:101655280-101682844 (+)
CBA/J ENSMUSG00210043903
 protein coding gene Chr7:98805741-98833166 (+)
DBA/2J ENSMUSG00185021559
 protein coding gene Chr7:103155876-103183297 (+)
FVB/NJ ENSMUSG00205040452
 protein coding gene Chr7:98768146-98795571 (+)
JF1/MsJ ENSUMUG00000042837
 protein coding gene Chr7:108167557-108195076 (+)
LP/J ENSMUSG00230042151
 protein coding gene Chr7:109256973-109284394 (+)
NOD/ShiLtJ ENSMUSG00190042388
 protein coding gene Chr7:98967286-98994702 (+)
NZO/HlLtJ ENSMUSG00225014507
 protein coding gene Chr7:107479812-107507254 (+)
PWK/PhJ ENSLUMG00010038989
 protein coding gene Chr7:97300609-97328152 (+)
SPRET/EiJ ENSMSPG00010039855
 protein coding gene Chr7:98471909-98499107 (+)
WSB/EiJ ENSIUOG00005047139
 protein coding gene Chr7:99614046-99641531 (+)



Homology
more
  • Human Ortholog
    CTR9, CTR9 component of Paf1/RNA polymerase II complex
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CTR9, CTR9 component of Paf1/RNA polymerase II complex
  • Synonyms
    p150, p150TSP, SH2BP1, TSBP
  • Links
    NCBI Gene ID: 9646
    UniProt: Q6PD62

  • Chr Location
    11p15.4; chr11:10751018-10801625 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    44
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    605
  • Tissues
    7
  • cDNA Data
    145
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22083 NCBI Gene Model | MGI Sequence Detail 27427 C57BL/6J ±  kb
    transcript NM_009431 RefSeq | MGI Sequence Detail 4317 ZRU/MplStud  
    polypeptide Q62018 UniProt | EBI | MGI Sequence Detail 1173 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000006017 RNA polymerase-associated protein CTR9
      (term hierarchy)
    • InterPro Domains
      IPR031101 RNA polymerase-associated protein Ctr9
      IPR011990 Tetratricopeptide-like helical domain superfamily
      IPR019734 Tetratricopeptide repeat
      IPR056836 Tetratricopeptide repeat protein 21A/21B, fourth ARM domain
    • GlyGen
      Q62018 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 146
      cDNA 146
      Antibodies 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-33783, MGD-MRK-38390, MGI:2141821
    References
    more
    • Summaries
      All 63
      Developmental Gene Expression 2
      Gene Ontology 14
      Phenotypes 19
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    09/01/2026
    MGI 6.24     		The Jackson Laboratory