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Oaz1 Gene Detail
Summary
  • Symbol
    Oaz1
  • Name
    ornithine decarboxylase antizyme 1
  • Synonyms
    Antizyme, antizyme 1, AZ-1, AZ1
  • Feature Type
    protein coding gene
  • IDs
    MGI:109433
    NCBI Gene: 18245
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
  • Candidate for QTL
    3 QTL
Location &
Maps
more
  • Sequence Map
    Chr10:80662516-80665124 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109433
 protein coding gene Chr10:80662490-80665124 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017522
 protein coding gene Chr10:81486696-81491322 (+)
A/J MGP_AJ_G0017500
 protein coding gene Chr10:78618993-78621521 (+)
AKR/J MGP_AKRJ_G0017461
 protein coding gene Chr10:80773075-80776347 (+)
BALB/cJ MGP_BALBcJ_G0017462
 protein coding gene Chr10:78833066-78837503 (+)
C3H/HeJ MGP_C3HHeJ_G0017285
 protein coding gene Chr10:80859415-80862053 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017916
 protein coding gene Chr10:84284459-84287304 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015605
 protein coding gene Chr10:74829638-74832278 (+)
CAST/EiJ MGP_CASTEiJ_G0016852
 protein coding gene Chr10:81091908-81094538 (+)
CBA/J MGP_CBAJ_G0017257
 protein coding gene Chr10:87561743-87564381 (+)
DBA/2J MGP_DBA2J_G0017363
 protein coding gene Chr10:77816593-77819888 (+)
FVB/NJ MGP_FVBNJ_G0017357
 protein coding gene Chr10:77048330-77050964 (+)
LP/J MGP_LPJ_G0017434
 protein coding gene Chr10:81946450-81950825 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017383
 protein coding gene Chr10:89473650-89476258 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017957
 protein coding gene Chr10:80769950-80772478 (+)
PWK/PhJ MGP_PWKPhJ_G0016633
 protein coding gene Chr10:77710119-77712754 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016423
 protein coding gene Chr10:79718050-79720678 (+)
WSB/EiJ MGP_WSBEiJ_G0016912
 protein coding gene Chr10:80803169-80806846 (+)



Homology
more
  • Human Ortholog
    OAZ1, ornithine decarboxylase antizyme 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OAZ1, ornithine decarboxylase antizyme 1
  • Synonyms
    AZ1, AZI, OAZ
  • Links
    NCBI Gene ID: 4946
    neXtProt AC: NX_P54368
    UniProt: P54368

  • Chr Location
    19p13.3; chr19:2269486-2273490 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human OAZ1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    877
  • Tissues
    152
  • cDNA Data
    690
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035242 Ensembl Gene Model | MGI Sequence Detail 2609 C57BL/6J ±  kb
transcript ENSMUST00000180036 Ensembl | MGI Sequence Detail 1044 Not Applicable  
polypeptide ENSMUSP00000137400 Ensembl | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 696
    Genomic 2
    cDNA 691
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-38478
References
more
  • Summaries
    All 53
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:229060 Franzoni E, et al., miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory