Mvwf QTL Detail

Summary

• Symbol
  Mvwf
• Name
  modifier of von Willebrand factor

• Feature Type
  QTL
• IDs
  MGI:109512
  NCBI Gene: 112274

Location &
Maps

• Sequence Map
  Chr11:95459644-96176602 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 2 alleles in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

The RIIIS/J strain has prolonged bleeding time attributed to a deficiency in von Willebrand factor. This phenotype is largely accounted for by the Mfwf modifier locus.

Sequences &
Gene Models

• NCBI Gene
  112274

Other
Accession IDs

MGD-MRK-39511

References

• Summaries
  All 6

  Phenotypes 2
• Earliest
  J:37436 Mohlke KL, et al., A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11. Proc Natl Acad Sci U S A. 1996 Dec 24;93(26):15352-7
• Latest
  J:155708 Shavit JA, et al., Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice. Blood. 2009 Dec 17;114(26):5368-74