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Tuba1c Gene Detail
Summary
  • Symbol
    Tuba1c
  • Name
    tubulin, alpha 1C
  • Synonyms
    M[a]6, Tuba6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1095409
    NCBI Gene: 22146
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:98927772-98935986 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 55.61 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    293 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1095409
 protein coding gene Chr15:98927772-98935991 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022319
 protein coding gene Chr15:100820482-100828511 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0022253
 protein coding gene Chr15:99810720-99817811 (+)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0020108
 protein coding gene Chr12:51457090-51459978 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025773
 protein coding gene Chr3:152512247-152533036 (+)
CAST/EiJ MGP_CASTEiJ_G0021575
 protein coding gene Chr15:100721420-100729532 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0022127
 protein coding gene Chr15:95259717-95266954 (+)
LP/J MGP_LPJ_G0019622
 protein coding gene Chr12:49934602-49938298 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0023539
 protein coding gene Chr17:2254116-2257951 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0019068
 protein coding gene Chr12:49568383-49570439 (-)



Homology
more
  • Human Ortholog
    TUBA1C, tubulin alpha 1c
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TUBA1C, tubulin alpha 1c
  • Synonyms
    bcm948, TUBA6
  • Links
    NCBI Gene ID: 84790
    neXtProt AC: NX_Q9BQE3
    UniProt: Q9BQE3

  • Chr Location
    12q13.12; chr12:49188736-49274600 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    280
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22146 NCBI Gene Model | MGI Sequence Detail 8215 C57BL/6J ±  kb
    transcript NM_009448 RefSeq | MGI Sequence Detail 1977 C57BL/6  
    polypeptide P68373 UniProt | EBI | MGI Sequence Detail 449 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 281
      cDNA 280
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 8
      Phenotypes 30
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory