Pgame2 Gene Detail

Summary

• Symbol
  Pgame2
• Name
  phosphoglycerate mutase elevated 2
• Synonyms
  Pgam2e

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:109641
  NCBI Gene: 110381
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 4, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for this radiation-induced mutation are lethal. Heterozygous mutant mice are overtly normal and exhibit elevated phosphoglycerate mutase activity in blood but not in liver, lung, kidneys, spleen, heart, or brain.

Sequences &
Gene Models

• NCBI Gene
  110381

Other
Accession IDs

MGD-MRK-39640

References

• Summaries
  All 4

  Phenotypes 2
• Earliest
  J:19836 Pretsch W, et al., Estimates of the radiation-induced mutation frequencies to recessive visible, dominant cataract and enzyme-activity alleles in germ cells of AKR, BALB/c, DBA/2 and (102xC3H)F1 mice. Mutagenesis. 1994 Jul;9(4):289-94
• Latest
  J:39310 Pretsch W, et al., A second locus encoding elevated phosphoglycerate mutase activity (Pgam2e) maps to mouse chromosome 4. Mamm Genome. 1997 Apr;8(4):296-7