About   Help   FAQ
Cetn3 Gene Detail
Summary
  • Symbol
    Cetn3
  • Name
    centrin 3
  • Synonyms
    MmCEN3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1097706
    NCBI Gene: 12626
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:81931196-81945274 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 43.68 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    424 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1097706
 protein coding gene Chr13:81928201-81945274 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020790
 protein coding gene Chr13:82549971-82563813 (+)
A/J MGP_AJ_G0020746
 protein coding gene Chr13:79682928-79696780 (+)
AKR/J MGP_AKRJ_G0020719
 protein coding gene Chr13:82031466-82045309 (+)
BALB/cJ MGP_BALBcJ_G0020742
 protein coding gene Chr13:80225167-80239020 (+)
C3H/HeJ MGP_C3HHeJ_G0020536
 protein coding gene Chr13:81778710-81792556 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021179
 protein coding gene Chr13:85232653-85247869 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018747
 protein coding gene Chr13:76140489-76154327 (+)
CAST/EiJ MGP_CASTEiJ_G0020054
 protein coding gene Chr13:80875011-80890353 (+)
CBA/J MGP_CBAJ_G0020495
 protein coding gene Chr13:88467482-88481336 (+)
DBA/2J MGP_DBA2J_G0020620
 protein coding gene Chr13:79325382-79339226 (+)
FVB/NJ MGP_FVBNJ_G0020600
 protein coding gene Chr13:78413135-78426980 (+)
LP/J MGP_LPJ_G0020693
 protein coding gene Chr13:82771253-82785019 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020629
 protein coding gene Chr13:87376620-87391931 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021219
 protein coding gene Chr13:81449146-81462987 (+)
PWK/PhJ MGP_PWKPhJ_G0019807
 protein coding gene Chr13:78243265-78257238 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019630
 protein coding gene Chr13:77692791-77707064 (+)
WSB/EiJ MGP_WSBEiJ_G0020111
 protein coding gene Chr13:81879905-81894170 (+)



Homology
more
  • Human Ortholog
    CETN3, centrin 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CETN3, centrin 3
  • Synonyms
    CDC31, CEN3
  • Links
    NCBI Gene ID: 1070
    neXtProt AC: NX_O15182
    UniProt: O15182

  • Chr Location
    5q14.3; chr5:90392257-90409766 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    16 phenotypes from multigenic genotypes
    10 phenotype references
  • All Mutations and Alleles
    14
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    8
  • Targeted
    4
  • Genomic Mutations
    1 involving Cetn3
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    13 strains or lines available
Homozygous null mice are viable and fertile with no signs of syndromic ciliopathy and no detectable defects in retinal photoreceptor development and function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    962
  • Tissues
    33
  • cDNA Data
    122
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021537 Ensembl Gene Model | MGI Sequence Detail 14079 C57BL/6J ±  kb
transcript ENSMUST00000022009 Ensembl | MGI Sequence Detail 1226 Not Applicable  
polypeptide ENSMUSP00000022009 Ensembl | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 123
    cDNA 122
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 43
    Developmental Gene Expression 5
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:293626 Allon G, et al., PRCD is concentrated at the base of photoreceptor outer segments and is involved in outer segment disc formation. Hum Mol Genet. 2019 Dec 15;28(24):4078-4088
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory