Kank3 Gene Detail

Summary

• Symbol
  Kank3
• Name
  KN motif and ankyrin repeat domains 3
• Synonyms
  0610013D04Rik, Ankrd47, D17Ertd288e

• Feature Type
  protein coding gene
• IDs
  MGI:1098615
  NCBI Gene: 80880
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr17:34029497-34041894 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 17.98 cM
• Mapping Data
  4 experiments

Strain
Comparison

• SNPs within 2kb
  1 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1098615	protein coding gene	Chr17:34029493-34041894 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0023537	protein coding gene	Chr17:33747440-33762531 (+)
A/J	MGP_AJ_G0023496	protein coding gene	Chr17:32589430-32601817 (+)
AKR/J	MGP_AKRJ_G0023462	protein coding gene	Chr17:32966050-32979681 (+)
BALB/cJ	MGP_BALBcJ_G0023500	protein coding gene	Chr17:32734971-32747585 (+)
C3H/HeJ	MGP_C3HHeJ_G0023263	protein coding gene	Chr17:33315074-33327578 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0023944	protein coding gene	Chr17:35004654-35018807 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0021417	protein coding gene	Chr17:30097429-30109914 (+)
CAST/EiJ	MGP_CASTEiJ_G0022765	protein coding gene	Chr17:33430106-33443300 (+)
CBA/J	MGP_CBAJ_G0023239	protein coding gene	Chr17:36395223-36407640 (+)
DBA/2J	MGP_DBA2J_G0023368	protein coding gene	Chr17:31967443-31980186 (+)
FVB/NJ	MGP_FVBNJ_G0023337	protein coding gene	Chr17:31824756-31837466 (+)
LP/J	MGP_LPJ_G0023446	protein coding gene	Chr17:34023678-34035989 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0023357	protein coding gene	Chr17:35453149-35466635 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023984	protein coding gene	Chr17:33302442-33314808 (+)
PWK/PhJ	MGP_PWKPhJ_G0022513	protein coding gene	Chr17:30861309-30874081 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0022329	protein coding gene	Chr17:31266191-31278616 (+)
WSB/EiJ	MGP_WSBEiJ_G0022824	protein coding gene	Chr17:33335294-33349299 (+)

Homology

• Human Ortholog
  KANK3, KN motif and ankyrin repeat domains 3

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KANK3, KN motif and ankyrin repeat domains 3
  
• Synonyms
  ANKRD47
• Links
  HGNC:24796

  NCBI Gene ID: 256949

  neXtProt AC: NX_Q6NY19

  UniProt: Q6NY19

  
  
• Chr Location
  19p13.2; chr19:8322584-8343262 (-)  GRCh38

---

• MGI Vertebrate Homology
  Kank3 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: KANK3
• Gene Tree
  Kank3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  40
• Endonuclease-mediated
  2
• Gene trapped
  36
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  40 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  6
• GO References
  3

Expression

• Assay Results
  726
• Tissues
  12
• cDNA Data
  52
• Literature Summary
  5

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase kank3
  ZFIN kank3

Sequences &
Gene Models

• All Sequences
  64
• RefSeq
  6
• UniProt
  9
• CCDS
  CCDS28630.1, CCDS89070.1

• Ensembl
  ENSMUSG00000042099 (Evidence)
• NCBI Gene
  80880

Representative Sequences			Length	Strain/Species
genomic	80880	NCBI Gene Model | MGI Sequence Detail	12398	C57BL/6J
transcript	NM_030697	RefSeq | MGI Sequence Detail	2652	ZRU/MplStud
polypeptide	Q9Z1P7	UniProt | EBI | MGI Sequence Detail	791	Not Applicable

Protein
Information

• UniProt
  9 Sequences
• Protein Ontology
  PR:000029567 KN motif and ankyrin repeat domain-containing protein 3
  (term hierarchy)
• PDB
  6TLH
• InterPro Domains
  IPR002110 Ankyrin repeat
  IPR036770 Ankyrin repeat-containing domain superfamily
  IPR021939 Kank N-terminal motif
  IPR047184 KN motif and ankyrin repeat domain-containing protein 1-4

Molecular
Reagents

• All nucleic 55

  cDNA 52

  Primer pair 3

  
  

  Microarray probesets 5

Other
Accession IDs

MGI:2149715

References

• Summaries
  All 40

  Developmental Gene Expression 5

  Gene Ontology 3

  Phenotypes 9
• Earliest
  J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
• Latest
  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Kank3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr143795	Chr17:34029489-34029503 (+)	-1 bp
Tssr143796	Chr17:34036679-34036690 (+)	7,188 bp
Tssr143797	Chr17:34036780-34036808 (+)	7,297 bp
Tssr143798	Chr17:34036809-34036840 (+)	7,328 bp