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Haspin Gene Detail
Summary
  • Symbol
    Haspin
  • Name
    histone H3 associated protein kinase
  • Synonyms
    Gsg2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194498
    NCBI Gene: 14841
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:73026311-73029120 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 45.25 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    43 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194498
protein coding gene Chr11:73026310-73029120 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018652
protein coding gene Chr11:73808172-73810979 (-)
A/J MGP_AJ_G0018620
protein coding gene Chr11:71037796-71040605 (-)
AKR/J MGP_AKRJ_G0018589
protein coding gene Chr11:73205020-73207828 (-)
BALB/cJ MGP_BALBcJ_G0018592
protein coding gene Chr11:71342417-71345224 (-)
C3H/HeJ MGP_C3HHeJ_G0018405
protein coding gene Chr11:73161293-73164100 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019043
protein coding gene Chr11:76048952-76051761 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016686
protein coding gene Chr11:67848665-67851459 (-)
CAST/EiJ MGP_CASTEiJ_G0017960
protein coding gene Chr11:73543149-73545958 (-)
CBA/J MGP_CBAJ_G0018377
protein coding gene Chr11:79408917-79411724 (-)
DBA/2J MGP_DBA2J_G0018486
protein coding gene Chr11:70666570-70669379 (-)
FVB/NJ MGP_FVBNJ_G0018477
protein coding gene Chr11:70215192-70217999 (-)
LP/J MGP_LPJ_G0018557
protein coding gene Chr11:74306976-74309783 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018500
protein coding gene Chr11:79924917-79927724 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019085
protein coding gene Chr11:73395248-73398055 (-)
PWK/PhJ MGP_PWKPhJ_G0017733
protein coding gene Chr11:71306238-71309045 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017523
protein coding gene Chr11:73111847-73114654 (-)
WSB/EiJ MGP_WSBEiJ_G0018014
protein coding gene Chr11:73141771-73144578 (-)



Homology
more
  • Human Ortholog
    HASPIN, histone H3 associated protein kinase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HASPIN, histone H3 associated protein kinase
  • Synonyms
    GSG2
  • Links
    NCBI Gene ID: 83903
    neXtProt AC: NX_Q8TF76
    UniProt: Q8TF76

  • Chr Location
    17p13.2; chr17:3723903-3726699 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a null mutation display disordered germ cells in the testes.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050107 Ensembl Gene Model | MGI Sequence Detail 2810 C57BL/6J ±  kb
transcript ENSMUST00000052140 Ensembl | MGI Sequence Detail 2810 Not Applicable  
polypeptide ENSMUSP00000055806 Ensembl | MGI Sequence Detail 754 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 3
Other
Accession IDs
less
MGI:5897981
References
more
  • Summaries
    All 51
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory