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Tsga8 Gene Detail
Summary
  • Symbol
    Tsga8
  • Name
    testis specific gene A8
  • Synonyms
    Halapx, Halap-X
  • Feature Type
    protein coding gene
  • IDs
    MGI:1194903
    NCBI Gene: 100502723
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:82530284-82531530 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 38.38 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1194903
 protein coding gene ChrX:82530280-82531530 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035886
 protein coding gene ChrX:79455038-79456284 (-)
A/J MGP_AJ_G0035871
 protein coding gene ChrX:79608729-79609921 (-)
AKR/J MGP_AKRJ_G0035789
 protein coding gene ChrX:81754111-81755366 (-)
BALB/cJ MGP_BALBcJ_G0035852
 protein coding gene ChrX:78370803-78372130 (-)
C3H/HeJ MGP_C3HHeJ_G0035562
 protein coding gene ChrX:79816938-79818355 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036383
 protein coding gene ChrX:81946090-81947336 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033214
 protein coding gene ChrX:78631290-78632763 (-)
CAST/EiJ MGP_CASTEiJ_G0034851
 protein coding gene ChrX:64809572-64810914 (-)
CBA/J MGP_CBAJ_G0035537
 protein coding gene ChrX:84108283-84109700 (-)
DBA/2J MGP_DBA2J_G0035692
 protein coding gene ChrX:79032716-79033998 (-)
FVB/NJ MGP_FVBNJ_G0035631
 protein coding gene ChrX:78429816-78431062 (-)
LP/J MGP_LPJ_G0035781
 protein coding gene ChrX:80304835-80306081 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035668
 protein coding gene ChrX:87383571-87384817 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036410
 protein coding gene ChrX:79247088-79248334 (-)
PWK/PhJ MGP_PWKPhJ_G0034549
 protein coding gene ChrX:62870648-62872002 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034379
 protein coding gene ChrX:65711594-65712846 (-)
WSB/EiJ MGP_WSBEiJ_G0034990
 protein coding gene ChrX:78155025-78156235 (-)



Homology
less
Human Diseases
more
  • Diseases
    1 with Tsga8 mouse models

Human Disease Mouse Models
      
IDs
 View 2 models
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout leads to male infertility owing to abnormal spermiogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000035522 Ensembl Gene Model | MGI Sequence Detail 1247 C57BL/6J ±  kb
    transcript ENSMUST00000049420 Ensembl | MGI Sequence Detail 1070 Not Applicable  
    polypeptide ENSMUSP00000043015 Ensembl | MGI Sequence Detail 238 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1926610
    References
    more
    • Summaries
      All 22
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 3
      Phenotypes 1
    • Earliest
      J:36973 Taketo MM, et al., Mapping of eight testis-specific genes to mouse chromosomes. Genomics. 1997 Nov 15;46(1):138-42
    • Latest
      J:342617 Dali O, et al., Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory