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Nsg2 Gene Detail
Summary
  • Symbol
    Nsg2
  • Name
    neuron specific gene family member 2
  • Synonyms
    P19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202070
    NCBI Gene: 18197
  • Alliance
    gene page
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:31950463-32009202 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 18.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1847 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202070
 protein coding gene Chr11:31949678-32009211 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018125
 protein coding gene Chr11:30170995-30232844 (+)
A/J MGP_AJ_G0018098
 protein coding gene Chr11:29043980-29102291 (+)
AKR/J MGP_AKRJ_G0018062
 protein coding gene Chr11:29962803-30020359 (+)
BALB/cJ MGP_BALBcJ_G0018067
 protein coding gene Chr11:29233435-29296204 (+)
C3H/HeJ MGP_C3HHeJ_G0017880
 protein coding gene Chr11:29906910-29968049 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018519
 protein coding gene Chr11:31170394-31230876 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016174
 protein coding gene Chr11:27569334-27628836 (+)
CAST/EiJ MGP_CASTEiJ_G0017442
 protein coding gene Chr11:29931804-29992724 (+)
CBA/J MGP_CBAJ_G0017853
 protein coding gene Chr11:32641568-32710319 (+)
DBA/2J MGP_DBA2J_G0017963
 protein coding gene Chr11:28842933-28901518 (+)
FVB/NJ MGP_FVBNJ_G0017957
 protein coding gene Chr11:28651441-28713030 (+)
LP/J MGP_LPJ_G0018035
 protein coding gene Chr11:30409381-30471085 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017981
 protein coding gene Chr11:33671943-33735690 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018560
 protein coding gene Chr11:30084171-30144765 (+)
PWK/PhJ MGP_PWKPhJ_G0017224
 protein coding gene Chr11:28988410-29048282 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017018
 protein coding gene Chr11:29780262-29841043 (+)
WSB/EiJ MGP_WSBEiJ_G0017494
 protein coding gene Chr11:29712978-29778727 (+)



Homology
more
  • Human Ortholog
    NSG2, neuronal vesicle trafficking associated 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NSG2, neuronal vesicle trafficking associated 2
  • Synonyms
    CALY3, HMP19
  • Links
    NCBI Gene ID: 51617
    neXtProt AC: NX_Q9Y328
    UniProt: Q9Y328

  • Chr Location
    5q35.2; chr5:174045706-174243501 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    806
  • Tissues
    33
  • cDNA Data
    18
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020297 Ensembl Gene Model | MGI Sequence Detail 58740 C57BL/6J ±  kb
    transcript ENSMUST00000020537 Ensembl | MGI Sequence Detail 2239 Not Applicable  
    polypeptide ENSMUSP00000020537 Ensembl | MGI Sequence Detail 171 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000060140 neuronal vesicle trafficking-associated protein 2
      (term hierarchy)
    • InterPro Domains
      IPR009431 Neuronal vesicle trafficking-associated protein
    Molecular
    Reagents
    less
    • All nucleic 21
      cDNA 20
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2144061, MGI:2144710
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 10
      Gene Ontology 8
      Phenotypes 11
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory