About   Help   FAQ
Prss39 Gene Detail
Summary
  • Symbol
    Prss39
  • Name
    serine protease 39
  • Synonyms
    Tesp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1270856
    NCBI Gene: 21755
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:34537493-34542143 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 13.29 cM, cytoband B
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    229 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1270856
 protein coding gene Chr1:34537491-34542144 (+)
129S1/SvImJ MGP_129S1SvImJ_G0015910
 protein coding gene Chr1:32893194-32898549 (+)
A/J MGP_AJ_G0015894
 protein coding gene Chr1:32103459-32108484 (+)
AKR/J MGP_AKRJ_G0015850
 protein coding gene Chr1:32493320-32501152 (+)
BALB/cJ MGP_BALBcJ_G0015848
 protein coding gene Chr1:31749682-31755682 (+)
C3H/HeJ MGP_C3HHeJ_G0015682
 protein coding gene Chr1:32687957-32694660 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016301
 protein coding gene Chr1:34389006-34394451 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014023
 protein coding gene Chr1:29261787-29266408 (+)
CAST/EiJ MGP_CASTEiJ_G0015262
 protein coding gene Chr1:32557661-32563475 (+)
CBA/J MGP_CBAJ_G0015653
 protein coding gene Chr1:35344653-35353287 (+)
DBA/2J MGP_DBA2J_G0015754
 protein coding gene Chr1:31428253-31433762 (+)
FVB/NJ MGP_FVBNJ_G0015756
 protein coding gene Chr1:30980300-30985439 (+)
LP/J MGP_LPJ_G0015824
 protein coding gene Chr1:33229562-33234952 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0015776
 protein coding gene Chr1:37601593-37608706 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016348
 protein coding gene Chr1:32485270-32492249 (+)
PWK/PhJ MGP_PWKPhJ_G0015045
 protein coding gene Chr1:31161382-31165779 (+)
SPRET/EiJ MGP_SPRETEiJ_G0014830
 protein coding gene Chr1:32631995-32633979 (-)
WSB/EiJ MGP_WSBEiJ_G0015324
 protein coding gene Chr1:32465236-32470928 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    12
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21755 NCBI Gene Model | MGI Sequence Detail 4651 C57BL/6J ±  kb
transcript NM_001360855 RefSeq | MGI Sequence Detail 1330 C57BL/6  
polypeptide O70169 UniProt | EBI | MGI Sequence Detail 367 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000016918 inactive testicular serine protease 1
    (term hierarchy)
  • InterPro Domains
    IPR001314 Peptidase S1A, chymotrypsin family
    IPR009003 Peptidase S1, PA clan
    IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
    IPR001254 Serine proteases, trypsin domain
    IPR018114 Serine proteases, trypsin family, histidine active site
    IPR033116 Serine proteases, trypsin family, serine active site
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:47342 Kohno N, et al., Two novel testicular serine proteases, TESP1 and TESP2, are present in the mouse sperm acrosome. Biochem Biophys Res Commun. 1998 Apr 28;245(3):658-65
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory