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Phf11d Gene Detail
Summary
  • Symbol
    Phf11d
  • Name
    PHD finger protein 11D
  • Synonyms
    D14Ertd668e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277133
    NCBI Gene: 219132
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:59584856-59602919 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 31.48 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    599 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277133
 protein coding gene Chr14:59584646-59608004 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021422
 protein coding gene Chr14:53638483-53657041 (-)
A/J MGP_AJ_G0021381
 protein coding gene Chr14:52521784-52538354 (-)
AKR/J MGP_AKRJ_G0021357
 protein coding gene Chr14:54263926-54371893 (-)
BALB/cJ MGP_BALBcJ_G0021385
 protein coding gene Chr14:52479690-52500177 (-)
C3H/HeJ MGP_C3HHeJ_G0021163
 protein coding gene Chr14:53911575-54047319 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021823
 protein coding gene Chr14:56105675-56330160 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019362
 protein coding gene Chr14:50586160-50630478 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0021130
 protein coding gene Chr14:57765492-57920853 (-)
DBA/2J MGP_DBA2J_G0021251
 protein coding gene Chr14:52069459-52209699 (-)
FVB/NJ MGP_FVBNJ_G0021232
 protein coding gene Chr14:51521859-51622020 (-)
LP/J MGP_LPJ_G0021328
 protein coding gene Chr14:54674214-54696831 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021261
 protein coding gene Chr14:57295501-57326279 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021847
 protein coding gene Chr14:53518607-53537433 (-)
PWK/PhJ MGP_PWKPhJ_G0020424
 protein coding gene Chr14:48801157-48831117 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020257
 protein coding gene Chr14:49459302-49534684 (-)
WSB/EiJ MGP_WSBEiJ_G0020733
 protein coding gene Chr14:53824312-53847511 (-)



Homology
more
  • Human Ortholog
    PHF11, PHD finger protein 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHF11, PHD finger protein 11
  • Synonyms
    APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34
  • Links
    NCBI Gene ID: 51131
    neXtProt AC: NX_Q9UIL8
    UniProt: Q9UIL8

  • Chr Location
    13q14.2; chr13:49495610-49528981 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    38
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    33
  • Targeted
    2
  • Genomic Mutations
    1 involving Phf11d
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    27 strains or lines available
Mice homozygous for an ENU mutated allele exhibit a change in the expression levels of immune response gene after LPS exposure.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    758
  • Tissues
    12
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000068245 Ensembl Gene Model | MGI Sequence Detail 18064 C57BL/6J ±  kb
transcript ENSMUST00000161031 Ensembl | MGI Sequence Detail 1130 Not Applicable  
polypeptide ENSMUSP00000125181 Ensembl | MGI Sequence Detail 337 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR034732 Extended PHD (ePHD) domain
    IPR051188 PHD-type Zinc Finger Domain-Containing Protein
    IPR011011 Zinc finger, FYVE/PHD-type
    IPR001965 Zinc finger, PHD-type
    IPR013083 Zinc finger, RING/FYVE/PHD-type
Molecular
Reagents
less
  • All nucleic 21
    cDNA 19
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:217094 Zhang Y, et al., Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant. Mamm Genome. 2014 Dec;25(11-12):573-82
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory