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Cnih1 Gene Detail
Summary
  • Symbol
    Cnih1
  • Name
    cornichon family AMPA receptor auxiliary protein 1
  • Synonyms
    Cnih
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277202
    NCBI Gene: 12793
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:47013024-47025814 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 24.29 cM, cytoband C1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    392 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277202
 protein coding gene Chr14:47013024-47025868 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021214
 protein coding gene Chr14:40462108-40475267 (-)
A/J MGP_AJ_G0021161
 protein coding gene Chr14:39255636-39267321 (-)
AKR/J MGP_AKRJ_G0021139
 protein coding gene Chr14:40779361-40792140 (-)
BALB/cJ MGP_BALBcJ_G0021165
 protein coding gene Chr14:39303500-39316942 (-)
C3H/HeJ MGP_C3HHeJ_G0020948
 protein coding gene Chr14:40569425-40581980 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021599
 protein coding gene Chr14:42216225-42229035 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019158
 protein coding gene Chr14:38627109-38639968 (-)
CAST/EiJ MGP_CASTEiJ_G0020473
 protein coding gene Chr14:37697550-37710256 (-)
CBA/J MGP_CBAJ_G0020914
 protein coding gene Chr14:43556649-43568352 (-)
DBA/2J MGP_DBA2J_G0021037
 protein coding gene Chr14:39155344-39168169 (-)
FVB/NJ MGP_FVBNJ_G0021022
 protein coding gene Chr14:38892919-38905673 (-)
LP/J MGP_LPJ_G0021107
 protein coding gene Chr14:40757392-40773111 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021047
 protein coding gene Chr14:42921766-42934556 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021632
 protein coding gene Chr14:40322149-40338190 (-)
PWK/PhJ MGP_PWKPhJ_G0020222
 protein coding gene Chr14:36030936-36043867 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020046
 protein coding gene Chr14:36459695-36473035 (-)
WSB/EiJ MGP_WSBEiJ_G0020529
 protein coding gene Chr14:40430181-40443753 (-)



Homology
more
  • Human Ortholog
    CNIH1, cornichon family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNIH1, cornichon family member 1
  • Synonyms
    CNIH, CNIH-1, CNIL, TGAM77
  • Links
    NCBI Gene ID: 10175
    neXtProt AC: NX_O95406
    UniProt: O95406

  • Chr Location
    14q22.2; chr14:54423561-54441391 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
The male homozygous mutant mice exhibited a decreased anxiety-like response during open field testing when compared with controls. The male mutants also exhibited decreased body weight, total tissue mass, and lean body mass.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    819
  • Tissues
    108
  • cDNA Data
    13
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12793 NCBI Gene Model | MGI Sequence Detail 12791 C57BL/6J ±  kb
    transcript NM_001355011 RefSeq | MGI Sequence Detail 1532 C57BL/6  
    polypeptide O35372 UniProt | EBI | MGI Sequence Detail 144 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 16
      cDNA 14
      Primer pair 1
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:53793 Hwang SY, et al., The mouse cornichon gene family. Dev Genes Evol. 1999 Feb;209(2):120-5
    • Latest
      J:313930 Tan L, et al., Overexpression of Long Non-coding RNA 4933425B07Rik Causes Urinary Malformations in Mice. Front Cell Dev Biol. 2021;9:594640
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory