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Cnih2 Gene Detail
Summary
  • Symbol
    Cnih2
  • Name
    cornichon family AMPA receptor auxiliary protein 2
  • Synonyms
    Cnil
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277225
    NCBI Gene: 12794
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5142896-5148549 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.24 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    126 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277225
 protein coding gene Chr19:5142896-5148549 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024692
 protein coding gene Chr19:2019926-2025459 (-)
A/J MGP_AJ_G0024658
 protein coding gene Chr19:1918539-1925871 (-)
AKR/J MGP_AKRJ_G0024631
 protein coding gene Chr19:1966437-1973532 (-)
BALB/cJ MGP_BALBcJ_G0024658
 protein coding gene Chr19:1913819-1919340 (-)
C3H/HeJ MGP_C3HHeJ_G0024426
 protein coding gene Chr19:1970481-1976002 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025105
 protein coding gene Chr19:2077101-2082680 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022535
 protein coding gene Chr19:1848297-1853830 (-)
CAST/EiJ MGP_CASTEiJ_G0023898
 protein coding gene Chr19:1994592-2001943 (-)
CBA/J MGP_CBAJ_G0024397
 protein coding gene Chr19:2158977-2165696 (-)
DBA/2J MGP_DBA2J_G0024525
 protein coding gene Chr19:1902625-1908496 (-)
FVB/NJ MGP_FVBNJ_G0024492
 protein coding gene Chr19:1904155-1909710 (-)
LP/J MGP_LPJ_G0024611
 protein coding gene Chr19:2016097-2021825 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024522
 protein coding gene Chr19:2041548-2047066 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025153
 protein coding gene Chr19:1970147-1975738 (-)
PWK/PhJ MGP_PWKPhJ_G0023644
 protein coding gene Chr19:1940259-1945883 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023449
 protein coding gene Chr19:1959159-1964727 (-)
WSB/EiJ MGP_WSBEiJ_G0023960
 protein coding gene Chr19:1977803-1983657 (-)



Homology
more
  • Human Ortholog
    CNIH2, cornichon family AMPA receptor auxiliary protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNIH2, cornichon family AMPA receptor auxiliary protein 2
  • Synonyms
    CNIH-2, Cnil
  • Links
    NCBI Gene ID: 254263
    neXtProt AC: NX_Q6PI25
    UniProt: Q6PI25

  • Chr Location
    11q13.2; chr11:66278175-66285301 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 3 genetic backgrounds
    4 phenotypes from multigenic genotypes
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    877
  • Tissues
    152
  • cDNA Data
    27
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12794 NCBI Gene Model | MGI Sequence Detail 5654 C57BL/6J ±  kb
    transcript NM_001302333 RefSeq | MGI Sequence Detail 1387 C57BL/6  
    polypeptide O35089 UniProt | EBI | MGI Sequence Detail 160 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 27
      Primer pair 2
      Other 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 6
      Gene Ontology 9
      Phenotypes 6
    • Earliest
      J:53793 Hwang SY, et al., The mouse cornichon gene family. Dev Genes Evol. 1999 Feb;209(2):120-5
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory