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Bcl2a1b Gene Detail
Summary
  • Symbol
    Bcl2a1b
  • Name
    B cell leukemia/lymphoma 2 related protein A1b
  • Synonyms
    A1-b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1278326
    NCBI Gene: 12045
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:89081326-89089891 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 47.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    121 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1278326
 protein coding gene Chr9:89081262-89089891 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035113
 protein coding gene Chr9:89851201-89856280 (+)
A/J no annotation
AKR/J MGP_AKRJ_G0035027
 protein coding gene Chr9:89055406-89067324 (+)
BALB/cJ MGP_BALBcJ_G0035086
 protein coding gene Chr9:86640567-86641415 (+)
C3H/HeJ MGP_C3HHeJ_G0034797
 protein coding gene Chr9:89486713-89487643 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035882
 protein coding gene Chr9:119924547-119925209 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0034927
 protein coding gene Chr9:86020951-86032261 (-)
FVB/NJ MGP_FVBNJ_G0034871
 protein coding gene Chr9:85079884-85084915 (-)
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0034912
 protein coding gene Chr9:97456356-97472989 (+)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0034229
 protein coding gene Chr9:89143992-89149670 (+)



Homology
more
  • Human Ortholog
    BCL2A1, BCL2 related protein A1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCL2A1, BCL2 related protein A1
  • Synonyms
    ACC-1, ACC1, ACC-2, ACC2, BCL2L5, BFL1, GRS, HBPA1
  • Links
    NCBI Gene ID: 597
    neXtProt AC: NX_Q16548
    UniProt: Q16548

  • Chr Location
    15q25.1; chr15:79960892-79971196 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from multigenic genotypes
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    959
  • Tissues
    99
  • cDNA Data
    5
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12045 NCBI Gene Model | MGI Sequence Detail 8566 C57BL/6J ±  kb
transcript NM_007534 RefSeq | MGI Sequence Detail 764 C57BL/6  
polypeptide NP_031560 RefSeq | MGI Sequence Detail 172 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR020717 Apoptosis regulator, Bcl-2, BH1 motif, conserved site
    IPR020726 Apoptosis regulator, Bcl-2, BH2 motif, conserved site
    IPR046371 Bcl-2, Bcl-2 homology region 1-3
    IPR026298 Bcl-2 family
    IPR002475 Bcl2-like
    IPR036834 Bcl-2-like superfamily
    IPR013282 Bcl-2-related protein A1
Molecular
Reagents
less
  • All nucleic 9
    Genomic 1
    cDNA 8

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:47747 Hatakeyama S, et al., Multiple gene duplication and expression of mouse bcl-2-related genes, A1. Int Immunol. 1998 May;10(5):631-7
  • Latest
    J:287191 Tan L, et al., Single-Cell Transcriptomics Identifies the Adaptation of Scart1(+) Vgamma6(+) T Cells to Skin Residency as Activated Effector Cells. Cell Rep. 2019 Jun 18;27(12):3657-3671.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory