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Cyp2c38 Gene Detail
Summary
  • Symbol
    Cyp2c38
  • Name
    cytochrome P450, family 2, subfamily c, polypeptide 38
  • Feature Type
    protein coding gene
  • IDs
    MGI:1306819
    NCBI Gene: 13097
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:39379109-39451519 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 34.03 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2049 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1306819
 protein coding gene Chr19:39378000-39451519 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025101
 protein coding gene Chr19:38513674-38572261 (-)
A/J MGP_AJ_G0025077
 protein coding gene Chr19:36605879-36663243 (-)
AKR/J MGP_AKRJ_G0025045
 protein coding gene Chr19:37840350-37895333 (-)
BALB/cJ MGP_BALBcJ_G0025075
 protein coding gene Chr19:36706506-36779062 (-)
C3H/HeJ MGP_C3HHeJ_G0024834
 protein coding gene Chr19:37922607-37996294 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025516
 protein coding gene Chr19:39552479-39615600 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0024300
 protein coding gene Chr19:37709114-37802050 (-)
CBA/J MGP_CBAJ_G0024811
 protein coding gene Chr19:41456016-41524588 (-)
DBA/2J MGP_DBA2J_G0024943
 protein coding gene Chr19:36458926-36524031 (-)
FVB/NJ MGP_FVBNJ_G0024904
 protein coding gene Chr19:36287589-36343771 (-)
LP/J MGP_LPJ_G0025029
 protein coding gene Chr19:38559742-38618521 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024935
 protein coding gene Chr19:41174168-41238086 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025574
 protein coding gene Chr19:37918949-37985823 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0023852
 protein coding gene Chr19:36709965-36821539 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CYP2C18, cytochrome P450 family 2 subfamily C member 18
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2C18, cytochrome P450 family 2 subfamily C member 18
  • Synonyms
    CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
  • Links
    NCBI Gene ID: 1562
    neXtProt AC: NX_P33260
    UniProt: P33260

  • Chr Location
    10q23.33; chr10:94683729-94736190 (+)  GRCh38
  • Human Ortholog
    CYP2C19, cytochrome P450 family 2 subfamily C member 19
  • Synonyms
    CPCJ, CYP2C, CYPIIC17, CYPIIC19, P450C2C, P450IIC19
  • Links
    NCBI Gene ID: 1557
    neXtProt AC: NX_P33261
    UniProt: P33261

  • Chr Location
    10q23.33; chr10:94762681-94855547 (+)  GRCh38
  • Human Ortholog
    CYP2C8, cytochrome P450 family 2 subfamily C member 8
  • Synonyms
    CPC8, CYP2C8DM, CYPIIC8, MP-12/MP-20
  • Links
    NCBI Gene ID: 1558
    neXtProt AC: NX_P10632
    UniProt: P10632

  • Chr Location
    10q23.33; chr10:95036772-95069497 (-)  GRCh38
  • Human Ortholog
    CYP2C9, cytochrome P450 family 2 subfamily C member 9
  • Synonyms
    CPC9, CYP2C, CYP2C10, CYPIIC9, P450-2C9, P450IIC9
  • Links
    NCBI Gene ID: 1559
    neXtProt AC: NX_P11712
    UniProt: P11712

  • Chr Location
    10q23.33; chr10:94938658-94990091 (+)  GRCh38
Human Diseases
more
  • Diseases
    21 with human CYP2C19,CYP2C8,CYP2C9 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
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IDs
IDs
IDs
IDs
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IDs
IDs
IDs
IDs
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IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    820
  • Tissues
    99
  • cDNA Data
    8
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13097 NCBI Gene Model | MGI Sequence Detail 72411 C57BL/6J ±  kb
    transcript NM_010002 RefSeq | MGI Sequence Detail 1760 C57BL/6  
    polypeptide P56655 UniProt | EBI | MGI Sequence Detail 490 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 8
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:49570 Luo G, et al., Cloning and expression of murine CYP2Cs and their ability to metabolize arachidonic acid. Arch Biochem Biophys. 1998 Sep 1;357(1):45-57
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory