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Krt31 Gene Detail
Summary
  • Symbol
    Krt31
  • Name
    keratin 31
  • Synonyms
    Ha1, Kha1, Krt1-1, MKHA-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1309993
    NCBI Gene: 16660
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99937472-99941377 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.39 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    201 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1309993
 protein coding gene Chr11:99937472-99941377 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019137
 protein coding gene Chr11:102792194-102796824 (-)
A/J MGP_AJ_G0019105
 protein coding gene Chr11:98453047-98456913 (-)
AKR/J MGP_AKRJ_G0019074
 protein coding gene Chr11:101497207-101501073 (-)
BALB/cJ MGP_BALBcJ_G0019079
 protein coding gene Chr11:98969585-98973445 (-)
C3H/HeJ MGP_C3HHeJ_G0018888
 protein coding gene Chr11:101692662-101696619 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019528
 protein coding gene Chr11:105958722-105963921 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017155
 protein coding gene Chr11:95905895-95909894 (-)
CAST/EiJ MGP_CASTEiJ_G0018442
 protein coding gene Chr11:102672330-102676455 (-)
CBA/J MGP_CBAJ_G0018857
 protein coding gene Chr11:110386650-110391900 (-)
DBA/2J MGP_DBA2J_G0018970
 protein coding gene Chr11:98026592-98031363 (-)
FVB/NJ MGP_FVBNJ_G0018959
 protein coding gene Chr11:97527457-97531366 (-)
LP/J MGP_LPJ_G0019038
 protein coding gene Chr11:103328566-103332471 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018990
 protein coding gene Chr11:110019436-110024296 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019566
 protein coding gene Chr11:101871985-101877844 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0017997
 protein coding gene Chr11:101565663-101570194 (-)
WSB/EiJ MGP_WSBEiJ_G0018491
 protein coding gene Chr11:101840653-101844572 (-)



Homology
more
  • Human Ortholog
    KRT31, keratin 31
  • Vertebrate Orthologs
    14
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT31, keratin 31
  • Synonyms
    Ha-1, HA1, hHa1, KRTHA1
  • Links
    NCBI Gene ID: 3881
    neXtProt AC: NX_Q15323
    UniProt: Q15323

  • Chr Location
    17q21.2; chr17:41393721-41397608 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    9
  • cDNA Data
    8
  • Literature Summary
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16660 NCBI Gene Model | MGI Sequence Detail 3906 C57BL/6J ±  kb
transcript NM_010659 RefSeq | MGI Sequence Detail 1581 Not Specified  
polypeptide Q61765 UniProt | EBI | MGI Sequence Detail 416 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR018039 Intermediate filament protein, conserved site
    IPR039008 Intermediate filament, rod domain
    IPR002957 Keratin, type I
Molecular
Reagents
less
  • All nucleic 11
    Genomic 3
    cDNA 8

    Microarray probesets 3
Other
Accession IDs
less
MGI:1099200
References
more
  • Summaries
    All 47
    Developmental Gene Expression 9
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:19077 Bertolino AP, et al., Cloning and characterization of a mouse type I hair keratin cDNA. J Invest Dermatol. 1988 Dec;91(6):541-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory