exma Gene Detail

Summary

• Symbol
  exma
• Name
  exencephaly and severe microphthalmia/anophthalmia
• Synonyms
  OVE597

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:1313145
  NCBI Gene: 14036
• Alliance
  gene page

Location &
Maps

• Sequence Map
  ChrX:81992476-93167308 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome X, cytoband C/D
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotypes from 1 allele in 1 genetic background
  1 images
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

Heterozygous mutant females exhibit reduced viability, patchy coat pigmentation and in some cases exencephaly and/or microphthalmia. Most hemizygous males exhibit an open, disorganized forebrain, fail to form optic vesicles and die at or before birth.

Sequences &
Gene Models

• NCBI Gene
  14036

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:76080 Cunningham D, et al., exma: an X-linked insertional mutation that disrupts forebrain and eye development. Mamm Genome. 2002 Apr;13(4):179-85