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Krtap8-1 Gene Detail
Summary
  • Symbol
    Krtap8-1
  • Name
    keratin associated protein 8-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330293
    NCBI Gene: 16703
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:89284267-89284840 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 51.42 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330293
 protein coding gene Chr16:89284262-89284840 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023020
 protein coding gene Chr16:90337118-90337709 (-)
A/J MGP_AJ_G0022988
 protein coding gene Chr16:86157174-86157752 (-)
AKR/J MGP_AKRJ_G0022958
 protein coding gene Chr16:88767654-88768232 (-)
BALB/cJ MGP_BALBcJ_G0022990
 protein coding gene Chr16:86679568-86680146 (-)
C3H/HeJ MGP_C3HHeJ_G0022751
 protein coding gene Chr16:89307921-89308499 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023437
 protein coding gene Chr16:93289783-93290361 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020939
 protein coding gene Chr16:83895489-83896063 (-)
CAST/EiJ MGP_CASTEiJ_G0022270
 protein coding gene Chr16:89799179-89799770 (-)
CBA/J MGP_CBAJ_G0022720
 protein coding gene Chr16:97246639-97247217 (-)
DBA/2J MGP_DBA2J_G0022854
 protein coding gene Chr16:86074251-86074829 (-)
FVB/NJ MGP_FVBNJ_G0022828
 protein coding gene Chr16:85180376-85180954 (-)
LP/J MGP_LPJ_G0022924
 protein coding gene Chr16:90020399-90020990 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022849
 protein coding gene Chr16:101907388-101907966 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023455
 protein coding gene Chr16:89257219-89257810 (-)
PWK/PhJ MGP_PWKPhJ_G0022015
 protein coding gene Chr16:86202977-86203568 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021845
 protein coding gene Chr16:88761003-88761594 (-)
WSB/EiJ MGP_WSBEiJ_G0022322
 protein coding gene Chr16:89476489-89477067 (-)



Homology
more
  • Human Ortholog
    KRTAP8-1, keratin associated protein 8-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP8-1, keratin associated protein 8-1
  • Synonyms
    KAP8.1
  • Links
    NCBI Gene ID: 337879
    neXtProt AC: NX_Q8IUC2
    UniProt: Q8IUC2

  • Chr Location
    21q22.11; chr21:30812697-30813274 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    25
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000059632 Ensembl Gene Model | MGI Sequence Detail 574 C57BL/6J ±  kb
    transcript ENSMUST00000072280 Ensembl | MGI Sequence Detail 574 Not Applicable  
    polypeptide ENSMUSP00000072129 Ensembl | MGI Sequence Detail 61 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 25

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2146415
    References
    more
    • Summaries
      All 32
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:44334 Aoki N, et al., Isolation and characterization of mouse high-glycine/tyrosine proteins. J Biol Chem. 1997 Nov 28;272(48):30512-8
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory