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Sprr2h Gene Detail
Summary
  • Symbol
    Sprr2h
  • Name
    small proline-rich protein 2H
  • Feature Type
    protein coding gene
  • IDs
    MGI:1330343
    NCBI Gene: 20762
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:92292992-92294631 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.14 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    124 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1330343
 protein coding gene Chr3:92292992-92294631 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027492
 protein coding gene Chr3:92829894-92831507 (+)
A/J MGP_AJ_G0027459
 protein coding gene Chr3:89909117-89910756 (+)
AKR/J MGP_AKRJ_G0027424
 protein coding gene Chr3:92009918-92011584 (+)
BALB/cJ MGP_BALBcJ_G0027468
 protein coding gene Chr3:89719634-89721300 (+)
C3H/HeJ MGP_C3HHeJ_G0027207
 protein coding gene Chr3:92235583-92237142 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027911
 protein coding gene Chr3:96365848-96367487 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025262
 protein coding gene Chr3:86551461-86553043 (+)
CAST/EiJ MGP_CASTEiJ_G0026655
 protein coding gene Chr3:91647605-91649241 (+)
CBA/J MGP_CBAJ_G0027182
 protein coding gene Chr3:99659670-99661282 (+)
DBA/2J MGP_DBA2J_G0027319
 protein coding gene Chr3:89228997-89230690 (+)
FVB/NJ MGP_FVBNJ_G0027287
 protein coding gene Chr3:87396135-87397774 (+)
LP/J MGP_LPJ_G0027428
 protein coding gene Chr3:94046994-94048580 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027311
 protein coding gene Chr3:105909783-105911421 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027970
 protein coding gene Chr3:91742766-91744405 (+)
PWK/PhJ MGP_PWKPhJ_G0026388
 protein coding gene Chr3:89116518-89118157 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026207
 protein coding gene Chr3:90065460-90067068 (+)
WSB/EiJ MGP_WSBEiJ_G0026737
 protein coding gene Chr3:92134174-92135813 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Sprr2h
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    3 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    4
  • cDNA Data
    8
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20762 NCBI Gene Model | MGI Sequence Detail 1640 C57BL/6J ±  kb
transcript NM_011474 RefSeq | MGI Sequence Detail 752 ZRU/MplStud  
polypeptide O70559 UniProt | EBI | MGI Sequence Detail 108 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    Genomic 6
    cDNA 8
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:2139775
References
more
  • Summaries
    All 32
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:113697 Gibbs S, et al., Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. Genomics. 1993 Jun;16(3):630-7
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory