Krtap13 Gene Detail

Summary

• Symbol
  Krtap13
• Name
  keratin associated protein 13
• Synonyms
  4C32

• Feature Type
  protein coding gene
• IDs
  MGI:1330835
  NCBI Gene: 16699
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr16:88547632-88548516 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, 51.40 cM, cytoband C3.3
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  123 from dbSNP Build 142
• Strain Annotations
  15

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1330835	protein coding gene	Chr16:88547632-88548523 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022991	protein coding gene	Chr16:89570219-89571918 (-)
A/J	MGP_AJ_G0022959	protein coding gene	Chr16:85412730-85413611 (-)
AKR/J	MGP_AKRJ_G0022929	protein coding gene	Chr16:88015574-88016938 (-)
BALB/cJ	MGP_BALBcJ_G0022961	protein coding gene	Chr16:85944848-85945729 (-)
C3H/HeJ	MGP_C3HHeJ_G0022723	protein coding gene	Chr16:88576270-88578199 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023408	protein coding gene	Chr16:92445766-92448252 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020912	protein coding gene	Chr16:83243972-83244924 (-)
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0022692	protein coding gene	Chr16:96410968-96413979 (-)
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0022895	protein coding gene	Chr16:89248309-89249917 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022820	protein coding gene	Chr16:100951207-100954931 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023426	protein coding gene	Chr16:88509527-88511086 (-)
PWK/PhJ	MGP_PWKPhJ_G0021988	protein coding gene	Chr16:85500048-85501412 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021818	protein coding gene	Chr16:88069397-88070278 (-)
WSB/EiJ	MGP_WSBEiJ_G0022293	protein coding gene	Chr16:88741713-88742865 (-)

Homology

• Human Ortholog
  KRTAP13-1, keratin associated protein 13-1

• Vertebrate Orthologs
  7

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTAP13-1, keratin associated protein 13-1
  
• Synonyms
  KAP13.1, KRTAP13.1
• Links
  HGNC:18924

  NCBI Gene ID: 140258

  neXtProt AC: NX_Q8IUC0

  UniProt: Q8IUC0

  
  
• Chr Location
  21q22.11

---

• Human Ortholog
  KRTAP13-2, keratin associated protein 13-2
  
• Synonyms
  KAP13-2
• Links
  HGNC:18923

  NCBI Gene ID: 337959

  neXtProt AC: NX_Q52LG2

  UniProt: Q52LG2

  
  
• Chr Location
  21q22.11; chr21:30371390-30372271 (-)  GRCh38

---

• Human Ortholog
  KRTAP13-3, keratin associated protein 13-3
  
• Synonyms
  KAP13.3
• Links
  HGNC:18925

  NCBI Gene ID: 337960

  neXtProt AC: NX_Q3SY46

  UniProt: Q3SY46

  
  
• Chr Location
  21q22.11; chr21:30425380-30425926 (-)  GRCh38

---

• Human Ortholog
  KRTAP13-4, keratin associated protein 13-4
  
• Synonyms
  KAP13.4
• Links
  HGNC:18926

  NCBI Gene ID: 284827

  neXtProt AC: NX_Q3LI77

  UniProt: Q3LI77

  
  
• Chr Location
  21q22.11; chr21:30430220-30431026 (+)  GRCh38

---

• MGI Vertebrate Homology
  Krtap13 stringent orthology
  4 human;1 mouse;3 rat
  
• HCOP
  vertebrate homology predictions: KRTAP13-1, KRTAP13-2, KRTAP13-3, KRTAP13-4
• Gene Tree
  Krtap13
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  4
• Endonuclease-mediated
  1
• Targeted
  2
• Genomic Mutations
  3 involving Krtap13
• Incidental Mutations
  APF
• Find Mice (IMSR)
  5 strains or lines available

Expression

• Assay Results
  737
• Tissues
  23
• cDNA Data
  6
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  25
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS28300.1

• Ensembl
  ENSMUSG00000050224 (Evidence)
• NCBI Gene
  16699

Representative Sequences			Length	Strain/Species
genomic	16699	NCBI Gene Model | MGI Sequence Detail	885	C57BL/6J
transcript	NM_010671	RefSeq | MGI Sequence Detail	902	ICR
polypeptide	NP_034801	RefSeq | MGI Sequence Detail	197	ICR

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR007951 Keratin-associated protein, PMG type

Molecular
Reagents

• All nucleic 8

  Genomic 1

  cDNA 6

  Primer pair 1

  
  

  Microarray probesets 3

References

• Summaries
  All 27

  Developmental Gene Expression 3

  Phenotypes 7
• Earliest
  J:48444 Takaishi M, et al., Isolation and characterization of a putative keratin-associated protein gene expressed in embryonic skin of mice. J Invest Dermatol. 1998 Jul;111(1):128-32
• Latest
  J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077