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Bcl7b Gene Detail
Summary
  • Symbol
    Bcl7b
  • Name
    B cell CLL/lymphoma 7B
  • Feature Type
    protein coding gene
  • IDs
    MGI:1332238
    NCBI Gene: 12054
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:135197226-135210706 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 75.04 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    385 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1332238
 protein coding gene Chr5:135197137-135210709 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030176
 protein coding gene Chr5:139669789-139683308 (+)
A/J MGP_AJ_G0030144
 protein coding gene Chr5:133696642-133710225 (+)
AKR/J MGP_AKRJ_G0030077
 protein coding gene Chr5:138041795-138055270 (+)
BALB/cJ MGP_BALBcJ_G0030154
 protein coding gene Chr5:135053649-135067213 (+)
C3H/HeJ MGP_C3HHeJ_G0029870
 protein coding gene Chr5:138604027-138617560 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030607
 protein coding gene Chr5:144900233-144913782 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027830
 protein coding gene Chr5:127991954-128007067 (+)
CAST/EiJ MGP_CASTEiJ_G0029279
 protein coding gene Chr5:138019321-138033991 (+)
CBA/J MGP_CBAJ_G0029840
 protein coding gene Chr5:150572599-150586125 (+)
DBA/2J MGP_DBA2J_G0029991
 protein coding gene Chr5:133597415-133610995 (+)
FVB/NJ MGP_FVBNJ_G0029946
 protein coding gene Chr5:132732028-132745678 (+)
LP/J MGP_LPJ_G0030079
 protein coding gene Chr5:140116120-140130386 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029978
 protein coding gene Chr5:153582623-153596164 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030647
 protein coding gene Chr5:137786793-137802603 (+)
PWK/PhJ MGP_PWKPhJ_G0028994
 protein coding gene Chr5:132639623-132653224 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028829
 protein coding gene Chr5:135351875-135365339 (+)
WSB/EiJ MGP_WSBEiJ_G0029353
 protein coding gene Chr5:138539186-138552818 (+)



Homology
more
  • Human Ortholog
    BCL7B, BAF chromatin remodeling complex subunit BCL7B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BCL7B, BAF chromatin remodeling complex subunit BCL7B
  • Synonyms
    SMARCJ2
  • Links
    NCBI Gene ID: 9275
    neXtProt AC: NX_Q9BQE9
    UniProt: Q9BQE9

  • Chr Location
    7q11.23; chr7:73536356-73557690 (-)  GRCh38
Human Diseases
less
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation are viable with no gross developmental, motor coordination, or memory formation abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    14
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    781
  • Tissues
    35
  • cDNA Data
    11
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12054 NCBI Gene Model | MGI Sequence Detail 13481 C57BL/6J ±  kb
    transcript NM_009745 RefSeq | MGI Sequence Detail 1678 C57BL/6  
    polypeptide Q921K9 UniProt | EBI | MGI Sequence Detail 202 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 21
      Genomic 5
      cDNA 11
      Primer pair 4
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 67
      Developmental Gene Expression 5
      Diseases 2
      Gene Ontology 14
      Phenotypes 27
    • Earliest
      J:35263 Wang W, et al., Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev. 1996 Sep 1;10(17):2117-30
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory