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Magea6 Gene Detail
Summary
  • Symbol
    Magea6
  • Name
    MAGE family member A6
  • Synonyms
    Mage-a6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333837
    NCBI Gene: 17142
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:153707008-153718983 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 72.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    374 from dbSNP Build 142
  • Strain Annotations
    7
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333837
 protein coding gene ChrX:153706891-153719070 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036208
 protein coding gene ChrX:152964553-152970406 (-)
A/J MGP_AJ_G0036180
 protein coding gene ChrX:152181493-152248964 (-)
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0035879
 protein coding gene ChrX:153102884-153105117 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0035854
 protein coding gene ChrX:161736989-161740172 (-)
DBA/2J MGP_DBA2J_G0036015
 protein coding gene ChrX:151043886-151044559 (-)
FVB/NJ MGP_FVBNJ_G0035950
 protein coding gene ChrX:150297458-150352110 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    MAGEA10, MAGE family member A10
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAGEA10, MAGE family member A10
  • Synonyms
    CT1.10, MAGE10
  • Links
    NCBI Gene ID: 4109
    neXtProt AC: NX_P43363
    UniProt: P43363

  • Chr Location
    Xq28; chrX:152133310-152138578 (-)  GRCh38
  • Human Ortholog
    MAGEA4, MAGE family member A4
  • Synonyms
    CT1.4, MAGE4, MAGE-41, MAGE4A, MAGE4B, MAGE-X2
  • Links
    NCBI Gene ID: 4103
    neXtProt AC: NX_P43358
    UniProt: P43358

  • Chr Location
    Xq28; chrX:151912474-151925171 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    757
  • Tissues
    32
  • cDNA Data
    4
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063728 Ensembl Gene Model | MGI Sequence Detail 11976 C57BL/6J ±  kb
transcript ENSMUST00000112562 Ensembl | MGI Sequence Detail 1212 Not Applicable  
polypeptide ENSMUSP00000108181 Ensembl | MGI Sequence Detail 325 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002190 MAGE homology domain
    IPR041898 MAGE homology domain, winged helix WH1 motif
    IPR041899 MAGE homology domain, winged helix WH2 motif
    IPR037445 Melanoma-associated antigen
Molecular
Reagents
less
  • All nucleic 6
    cDNA 4
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 10
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:52871 De Plaen E, et al., A new family of mouse genes homologous to the human MAGE genes. Genomics. 1999 Jan 15;55(2):176-84
  • Latest
    J:342299 Fon Tacer K, et al., MAGE cancer-testis antigens protect the mammalian germline under environmental stress. Sci Adv. 2019 May;5(5):eaav4832
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory