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Slc31a2 Gene Detail
Summary
  • Symbol
    Slc31a2
  • Name
    solute carrier family 31, member 2
  • Synonyms
    Ctr2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1333844
    NCBI Gene: 20530
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:62198630-62216649 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 33.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    505 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1333844
 protein coding gene Chr4:62180799-62216649 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028347
 protein coding gene Chr4:61264093-61274678 (+)
A/J MGP_AJ_G0028308
 protein coding gene Chr4:59045259-59057104 (+)
AKR/J MGP_AKRJ_G0028257
 protein coding gene Chr4:60681975-60693876 (+)
BALB/cJ MGP_BALBcJ_G0028328
 protein coding gene Chr4:59220371-59232555 (+)
C3H/HeJ MGP_C3HHeJ_G0028046
 protein coding gene Chr4:61187712-61198191 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028768
 protein coding gene Chr4:63369646-63382926 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026074
 protein coding gene Chr4:56338007-56351013 (+)
CAST/EiJ MGP_CASTEiJ_G0027482
 protein coding gene Chr4:59121584-59133323 (+)
CBA/J MGP_CBAJ_G0028013
 protein coding gene Chr4:65552288-65569060 (+)
DBA/2J MGP_DBA2J_G0028163
 protein coding gene Chr4:58902983-58914226 (+)
FVB/NJ MGP_FVBNJ_G0028128
 protein coding gene Chr4:58150139-58162275 (+)
LP/J MGP_LPJ_G0028260
 protein coding gene Chr4:61550348-61564009 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028155
 protein coding gene Chr4:68697340-68712135 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028804
 protein coding gene Chr4:60782177-60793354 (+)
PWK/PhJ MGP_PWKPhJ_G0027209
 protein coding gene Chr4:57379797-57390862 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027038
 protein coding gene Chr4:58222716-58234595 (+)
WSB/EiJ MGP_WSBEiJ_G0027562
 protein coding gene Chr4:60764887-60776406 (+)



Homology
more
  • Human Ortholog
    SLC31A2, solute carrier family 31 member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC31A2, solute carrier family 31 member 2
  • Synonyms
    COPT2, CTR2, hCTR2
  • Links
    NCBI Gene ID: 1318
    neXtProt AC: NX_O15432
    UniProt: O15432

  • Chr Location
    9q32; chr9:113150976-113164140 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    820
  • Tissues
    109
  • cDNA Data
    72
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20530 NCBI Gene Model | MGI Sequence Detail 18020 C57BL/6J ±  kb
transcript NM_025286 RefSeq | MGI Sequence Detail 1841 C57BL/6  
polypeptide Q9CPU9 UniProt | EBI | MGI Sequence Detail 143 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 75
    cDNA 74
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140341
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:51199 Nishihara E, et al., Expression of copper trafficking genes in the mouse brain. Neuroreport. 1998 Oct 5;9(14):3259-63
  • Latest
    J:346176 Haberkiewicz O, et al., Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease. Int J Mol Sci. 2022 Sep 28;23(19)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory