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Ppp2r3d Gene Detail
Summary
  • Symbol
    Ppp2r3d
  • Name
    protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
  • Synonyms
    Ppp2r3, Ppp2r3a, PR59
  • Feature Type
    protein coding gene
  • IDs
    MGI:1335093
    NCBI Gene: 19054
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:124195412-124204759 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    225 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1335093
 protein coding gene Chr9:124195310-124204759 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035495
 protein coding gene Chr9:127586918-127595207 (-)
A/J MGP_AJ_G0035474
 protein coding gene Chr9:122723127-122742659 (-)
AKR/J MGP_AKRJ_G0035407
 protein coding gene Chr9:126083825-126089712 (-)
BALB/cJ MGP_BALBcJ_G0035470
 protein coding gene Chr9:122617038-122625266 (-)
C3H/HeJ MGP_C3HHeJ_G0035176
 protein coding gene Chr9:126357693-126363566 (-)
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034480
 protein coding gene Chr9:126176846-126184994 (-)
CBA/J MGP_CBAJ_G0035145
 protein coding gene Chr9:135897724-135897981 (-)
DBA/2J MGP_DBA2J_G0035304
 protein coding gene Chr9:122247416-122251209 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0035383
 protein coding gene Chr9:127962905-127971182 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035292
 protein coding gene Chr9:136757451-136761817 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030340
 protein coding gene Chr5:110416783-110417043 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0033971
 protein coding gene Chr9:123374283-123374855 (+)
WSB/EiJ MGP_WSBEiJ_G0029054
 protein coding gene Chr5:110880904-110881157 (-)



Homology
more
  • Human Ortholog
    PPP2R3B, protein phosphatase 2 regulatory subunit B''beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP2R3B, protein phosphatase 2 regulatory subunit B''beta
  • Synonyms
    NYREN8, PPP2R3L, PPP2R3LY, PR48, PR70
  • Links
    NCBI Gene ID: 28227
    neXtProt AC: NX_Q9Y5P8
    UniProt: Q9Y5P8

  • Chr Location
    XY;Y
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    12
  • cDNA Data
    15
  • Literature Summary
    2
Sequences &
Gene Models
less
  • All Sequences
    74
  • RefSeq
    29
  • UniProt
    6
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000093803 Ensembl Gene Model | MGI Sequence Detail 9348 C57BL/6J ±  kb
transcript ENSMUST00000239563 Ensembl | MGI Sequence Detail 4449 Not Applicable  
polypeptide ENSMUSP00000159447 Ensembl | MGI Sequence Detail 525 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
    IPR041534 PP2A regulatory subunit B'', EF-hand domain
    IPR048855 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha/beta/delta, EF-hand
  • GlyGen
    Q9Z176 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:2142981
References
more
  • Summaries
    All 21
    Developmental Gene Expression 2
    Gene Ontology 7
  • Earliest
    J:52529 Voorhoeve PM, et al., Functional interaction between a novel protein phosphatase 2A regulatory subunit, PR59, and the retinoblastoma-related p107 protein. Oncogene. 1999 Jan 14;18(2):515-24
  • Latest
    J:239229 Nishi A, et al., Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution. J Biol Chem. 2017 Jan 27;292(4):1462-1476
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory