Gng10 MGI Mouse Gene Detail - MGI:1336169 - guanine nucleotide binding protein (G protein), gamma 10

Symbol

Gng10
Name

guanine nucleotide binding protein (G protein), gamma 10

Feature Type

protein coding gene
IDs

MGI:1336169
NCBI Gene: 14700
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr4:59035156-59041899 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 32.36 cM
Mapping Data

4 experiments

SNPs within 2kb

258 from dbSNP Build 142
Strain Annotations

18
RFLP

1

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1336169	protein coding gene	Chr4:59035088-59041903 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028332	protein coding gene	Chr4:57907424-57914080 (+)
A/J	MGP_AJ_G0028293	protein coding gene	Chr4:55683867-55690497 (+)
AKR/J	MGP_AKRJ_G0028242	protein coding gene	Chr4:57248452-57255068 (+)
BALB/cJ	MGP_BALBcJ_G0028312	protein coding gene	Chr4:55861058-55868017 (+)
C3H/HeJ	MGP_C3HHeJ_G0028033	protein coding gene	Chr4:57709189-57716564 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0028753	protein coding gene	Chr4:59947034-59954937 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026059	protein coding gene	Chr4:52429342-52436464 (+)
CAST/EiJ	MGP_CASTEiJ_G0027471	protein coding gene	Chr4:57486973-57495808 (+)
CBA/J	MGP_CBAJ_G0027998	protein coding gene	Chr4:61978743-61985411 (+)
DBA/2J	MGP_DBA2J_G0028148	protein coding gene	Chr4:55595349-55601963 (+)
FVB/NJ	MGP_FVBNJ_G0028115	protein coding gene	Chr4:54800415-54807507 (+)
LP/J	MGP_LPJ_G0028247	protein coding gene	Chr4:58006869-58013457 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028139	protein coding gene	Chr4:65103641-65110312 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028789	protein coding gene	Chr4:57432511-57439113 (+)
PWK/PhJ	MGP_PWKPhJ_G0027196	protein coding gene	Chr4:55608329-55615023 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027024	protein coding gene	Chr4:56766412-56772979 (+)
WSB/EiJ	MGP_WSBEiJ_G0027549	protein coding gene	Chr4:57413745-57421486 (+)

Human Ortholog

GNG10, G protein subunit gamma 10

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GNG10, G protein subunit gamma 10
Links

HGNC:4402

NCBI Gene ID: 2790

neXtProt AC: NX_P50151

UniProt: P50151
Chr Location

9q31.3; chr9:111661605-111670226 (+) GRCh38

MGI Vertebrate Homology

Gng10 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: GNG10
Gene Tree

Gng10

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Phenotype Summary

1 phenotype reference

All Mutations and Alleles

1
Endonuclease-mediated

1
Incidental Mutations

APF
Find Mice (IMSR)

4 strains or lines available

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All GO Annotations

7
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

995
Tissues

14
cDNA Data

47
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GENSAT

GEO

Expression Atlas
Other Vertebrate Links

Xenbase gng10

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All Sequences

35
RefSeq

2
UniProt

1
CCDS

CCDS18217.1

Ensembl

ENSMUSG00000038607 (Evidence)
NCBI Gene

14700

			Length	Strain/Species	Flank
genomic	14700	NCBI Gene Model \| MGI Sequence Detail	6744	C57BL/6J	± kb
transcript	NM_025277	RefSeq \| MGI Sequence Detail	1120	ZRU/MplStud
polypeptide	Q9CXP8	UniProt \| EBI \| MGI Sequence Detail	68	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000008103 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10

(term hierarchy)
InterPro Domains

IPR015898 G-protein gamma-like domain

IPR036284 G-protein gamma-like domain superfamily

IPR001770 G-protein, gamma subunit

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All nucleic 47

cDNA 47

Microarray probesets 2

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MGI:2140510

Summaries

All 26

Developmental Gene Expression 3

Gene Ontology 3

Phenotypes 1
Earliest

J:54663 Downes GB, et al., Chromosomal mapping of five mouse G protein gamma subunits. Genomics. 1999 Apr 1;57(1):173-6
Latest

J:215128 Moon AM, et al., Disruption of G-protein gamma5 subtype causes embryonic lethality in mice. PLoS One. 2014;9(3):e90970

TSS for Gng10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr37408	Chr4:59033205-59033217 (+)	-1,945 bp
Tssr37409	Chr4:59035175-59035247 (+)	55 bp
Tssr1186	Chr4:59035250-59035261 (+)	100 bp
Tssr37410	Chr4:59035464-59035478 (+)	315 bp
Tssr37411	Chr4:59035493-59035501 (+)	341 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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