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Car11 Gene Detail
Summary
  • Symbol
    Car11
  • Name
    carbonic anhydrase 11
  • Synonyms
    CA-RP XI
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336193
    NCBI Gene: 12348
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:45349267-45354106 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 29.44 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    159 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336193
 protein coding gene Chr7:45348537-45354106 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032240
 protein coding gene Chr7:46007948-46013223 (+)
A/J MGP_AJ_G0032219
 protein coding gene Chr7:45095870-45100630 (+)
AKR/J MGP_AKRJ_G0032155
 protein coding gene Chr7:46345553-46352726 (+)
BALB/cJ MGP_BALBcJ_G0032231
 protein coding gene Chr7:45090583-45095378 (+)
C3H/HeJ MGP_C3HHeJ_G0031946
 protein coding gene Chr7:46842209-46846984 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032723
 protein coding gene Chr7:48259046-48263838 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029737
 protein coding gene Chr7:47649909-47654663 (+)
CAST/EiJ MGP_CASTEiJ_G0031275
 protein coding gene Chr7:38280479-38287246 (+)
CBA/J MGP_CBAJ_G0031911
 protein coding gene Chr7:49868801-49873593 (+)
DBA/2J MGP_DBA2J_G0032069
 protein coding gene Chr7:44776337-44781254 (+)
FVB/NJ MGP_FVBNJ_G0032020
 protein coding gene Chr7:44548707-44553939 (+)
LP/J MGP_LPJ_G0032147
 protein coding gene Chr7:46711195-46717886 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032057
 protein coding gene Chr7:48549771-48554563 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032739
 protein coding gene Chr7:45559162-45563953 (+)
PWK/PhJ MGP_PWKPhJ_G0030997
 protein coding gene Chr7:38142805-38148168 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030835
 protein coding gene Chr7:33586849-33594737 (+)
WSB/EiJ MGP_WSBEiJ_G0031392
 protein coding gene Chr7:46063435-46068237 (+)



Homology
more
  • Human Ortholog
    CA11, carbonic anhydrase 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CA11, carbonic anhydrase 11
  • Synonyms
    CA-RP, CARP-2, CA-RP II, CARPX1, CA-XI
  • Links
    NCBI Gene ID: 770
    neXtProt AC: NX_O75493
    UniProt: O75493

  • Chr Location
    19q13.33; chr19:48637946-48646187 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    963
  • Tissues
    146
  • cDNA Data
    26
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003273 Ensembl Gene Model | MGI Sequence Detail 4840 C57BL/6J ±  kb
transcript ENSMUST00000003360 Ensembl | MGI Sequence Detail 1585 Not Applicable  
polypeptide ENSMUSP00000003360 Ensembl | MGI Sequence Detail 328 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004914 carbonic anhydrase-related protein 11
    (term hierarchy)
  • InterPro Domains
    IPR001148 Alpha carbonic anhydrase domain
    IPR036398 Alpha carbonic anhydrase domain superfamily
    IPR023561 Carbonic anhydrase, alpha-class
    IPR041878 Carbonic anhydrase-related protein X/XI
  • GlyGen
    O70354 3 sites, 7 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 29
    cDNA 26
    Primer pair 3

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 7
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:52003 Lovejoy DA, et al., Evolutionarily conserved, acatalytic carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. Genomics. 1998 Dec 15;54(3):484-93
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory