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Fkbp7 Gene Detail
Summary
  • Symbol
    Fkbp7
  • Name
    FK506 binding protein 7
  • Synonyms
    FKBP23
  • Feature Type
    protein coding gene
  • IDs
    MGI:1336879
    NCBI Gene: 14231
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:76493378-76503442 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 45.09 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    378 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1336879
 protein coding gene Chr2:76493378-76503460 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025868
 protein coding gene Chr2:77057823-77067756 (-)
A/J MGP_AJ_G0025845
 protein coding gene Chr2:74070300-74080200 (-)
AKR/J MGP_AKRJ_G0025814
 protein coding gene Chr2:76061826-76073307 (-)
BALB/cJ MGP_BALBcJ_G0025840
 protein coding gene Chr2:74244922-74254977 (-)
C3H/HeJ MGP_C3HHeJ_G0025600
 protein coding gene Chr2:76266039-76276114 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026287
 protein coding gene Chr2:79345177-79355291 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023690
 protein coding gene Chr2:71473889-71484045 (-)
CAST/EiJ MGP_CASTEiJ_G0025062
 protein coding gene Chr2:76604170-76614318 (-)
CBA/J MGP_CBAJ_G0025581
 protein coding gene Chr2:82280791-82290860 (-)
DBA/2J MGP_DBA2J_G0025712
 protein coding gene Chr2:73658487-73668533 (-)
FVB/NJ MGP_FVBNJ_G0025674
 protein coding gene Chr2:73050800-73064947 (-)
LP/J MGP_LPJ_G0025800
 protein coding gene Chr2:76941793-76951852 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025705
 protein coding gene Chr2:84102020-84112129 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026343
 protein coding gene Chr2:76187223-76198005 (-)
PWK/PhJ MGP_PWKPhJ_G0024805
 protein coding gene Chr2:73620308-73630940 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024611
 protein coding gene Chr2:76436582-76446551 (-)
WSB/EiJ MGP_WSBEiJ_G0025131
 protein coding gene Chr2:76656638-76666708 (-)



Homology
more
  • Human Ortholog
    FKBP7, FKBP prolyl isomerase 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FKBP7, FKBP prolyl isomerase 7
  • Synonyms
    FKBP23, PPIase
  • Links
    NCBI Gene ID: 51661
    neXtProt AC: NX_Q9Y680
    UniProt: Q9Y680

  • Chr Location
    2q31.2; chr2:178463664-178478600 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    883
  • Tissues
    53
  • cDNA Data
    27
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 14231 NCBI Gene Model | MGI Sequence Detail 10065 C57BL/6J ±  kb
transcript NM_001355080 RefSeq | MGI Sequence Detail 1014 ZRU/MplStud  
polypeptide O54998 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007543 peptidyl-prolyl cis-trans isomerase FKBP7
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR018247 EF-Hand 1, calcium-binding site
    IPR002048 EF-hand domain
    IPR011992 EF-hand domain pair
    IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain
    IPR046357 Peptidyl-prolyl cis-trans isomerase domain superfamily
    IPR052273 Peptidyl-prolyl cis-trans isomerase FKBP
  • GlyGen
    O54998 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 30
    cDNA 28
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:51036 Nakamura T, et al., Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability. Genomics. 1998 Nov 15;54(1):89-98
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory