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Cdyl Gene Detail
Summary
  • Symbol
    Cdyl
  • Name
    chromodomain protein, Y chromosome-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:1339956
    NCBI Gene: 12593
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:35843816-36058046 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 14.39 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5839 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1339956
 protein coding gene Chr13:35843801-36058047 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020458
 protein coding gene Chr13:33840810-34060958 (+)
A/J MGP_AJ_G0020412
 protein coding gene Chr13:32829049-33043197 (+)
AKR/J MGP_AKRJ_G0020390
 protein coding gene Chr13:33622975-33853993 (+)
BALB/cJ MGP_BALBcJ_G0020408
 protein coding gene Chr13:32890580-33106822 (+)
C3H/HeJ MGP_C3HHeJ_G0020207
 protein coding gene Chr13:33505891-33727114 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020841
 protein coding gene Chr13:34980717-35212302 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018428
 protein coding gene Chr13:31057452-31265090 (+)
CAST/EiJ MGP_CASTEiJ_G0019722
 protein coding gene Chr13:33204476-33441034 (+)
CBA/J MGP_CBAJ_G0020168
 protein coding gene Chr13:36476230-36710584 (+)
DBA/2J MGP_DBA2J_G0020290
 protein coding gene Chr13:32349019-32567256 (+)
FVB/NJ MGP_FVBNJ_G0020269
 protein coding gene Chr13:31895531-32106859 (+)
LP/J MGP_LPJ_G0020365
 protein coding gene Chr13:34074886-34301284 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020299
 protein coding gene Chr13:36643149-36878453 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020884
 protein coding gene Chr13:33234439-33455495 (+)
PWK/PhJ MGP_PWKPhJ_G0019477
 protein coding gene Chr13:32457967-32677216 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019308
 protein coding gene Chr13:31940185-32172156 (+)
WSB/EiJ MGP_WSBEiJ_G0019784
 protein coding gene Chr13:33596933-33821896 (+)



Homology
more
  • Human Ortholog
    CDYL, chromodomain Y like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDYL, chromodomain Y like
  • Synonyms
    CDYL1
  • Links
    NCBI Gene ID: 9425
    neXtProt AC: NX_Q9Y232
    UniProt: Q9Y232

  • Chr Location
    6p25.1; chr6:4706138-4955551 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Cdyl mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    57
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    5
  • Gene trapped
    49
  • Targeted
    2
  • Genomic Mutations
    1 involving Cdyl
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    71 strains or lines available
Conditional homozygous knockout in the cerebral cortex affects neuronal migration and results in increased susceptibility to pharmacologically induced seizures.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    41
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    748
  • Tissues
    5
  • cDNA Data
    15
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000059288 Ensembl Gene Model | MGI Sequence Detail 214231 C57BL/6J ±  kb
transcript ENSMUST00000075220 Ensembl | MGI Sequence Detail 3470 Not Applicable  
polypeptide ENSMUSP00000074707 Ensembl | MGI Sequence Detail 593 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2145214
References
more
  • Summaries
    All 59
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 10
    Phenotypes 19
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:358017 Yang Y, et al., The chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin. Cell Rep. 2024 Oct 22;43(10):114814
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory