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Hmg20b Gene Detail
Summary
  • Symbol
    Hmg20b
  • Name
    high mobility group 20B
  • Synonyms
    BRAF35, BRCA2-associated factor 35, Hmgx2, Hmgxb2, Smarce1r
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341190
    NCBI Gene: 15353
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81181882-81186314 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341190
 protein coding gene Chr10:81181880-81186777 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017553
 protein coding gene Chr10:82058410-82062842 (-)
A/J MGP_AJ_G0017531
 protein coding gene Chr10:79149861-79154293 (-)
AKR/J MGP_AKRJ_G0017492
 protein coding gene Chr10:81324630-81329062 (-)
BALB/cJ MGP_BALBcJ_G0017493
 protein coding gene Chr10:79369698-79374130 (-)
C3H/HeJ MGP_C3HHeJ_G0017316
 protein coding gene Chr10:81425053-81429485 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017947
 protein coding gene Chr10:84875602-84880034 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015636
 protein coding gene Chr10:75347112-75351480 (-)
CAST/EiJ MGP_CASTEiJ_G0016883
 protein coding gene Chr10:81653500-81657948 (-)
CBA/J MGP_CBAJ_G0017288
 protein coding gene Chr10:88191421-88195853 (-)
DBA/2J MGP_DBA2J_G0017394
 protein coding gene Chr10:78354505-78358789 (-)
FVB/NJ MGP_FVBNJ_G0017388
 protein coding gene Chr10:77603268-77608969 (-)
LP/J MGP_LPJ_G0017465
 protein coding gene Chr10:82505624-82510056 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017414
 protein coding gene Chr10:90031901-90036333 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017988
 protein coding gene Chr10:81334255-81338687 (-)
PWK/PhJ MGP_PWKPhJ_G0016664
 protein coding gene Chr10:78248181-78252693 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016454
 protein coding gene Chr10:80276709-80281160 (-)
WSB/EiJ MGP_WSBEiJ_G0016943
 protein coding gene Chr10:81366561-81370993 (-)



Homology
more
  • Human Ortholog
    HMG20B, high mobility group 20B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HMG20B, high mobility group 20B
  • Synonyms
    BRAF25, BRAF35, HMGX2, HMGXB2, PP7706, pp8857, SMARCE1r, SOXL
  • Links
    NCBI Gene ID: 10362
    neXtProt AC: NX_Q9P0W2
    UniProt: Q9P0W2

  • Chr Location
    19p13.3; chr19:3572777-3579088 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    890
  • Tissues
    178
  • cDNA Data
    86
  • Literature Summary
    12
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020232 Ensembl Gene Model | MGI Sequence Detail 4433 C57BL/6J ±  kb
transcript ENSMUST00000105323 Ensembl | MGI Sequence Detail 1463 Not Applicable  
polypeptide ENSMUSP00000100960 Ensembl | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000008627 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
    (term hierarchy)
  • PDB
    2CRJ
  • InterPro Domains
    IPR051965 Chromatin Regulation and Neuronal Gene Expression
    IPR009071 High mobility group box domain
    IPR036910 High mobility group box domain superfamily
Molecular
Reagents
less
  • All nucleic 87
    cDNA 86
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143872
References
more
  • Summaries
    All 53
    Developmental Gene Expression 12
    Gene Ontology 10
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory