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Uri1 Gene Detail
Summary
  • Symbol
    Uri1
  • Name
    URI1, prefoldin-like chaperone
  • Synonyms
    C80913, NNX3, Rmp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1342294
    NCBI Gene: 19777
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:37659417-37722976 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 25.29 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1636 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1342294
 protein coding gene Chr7:37659417-37722989 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032099
 protein coding gene Chr7:37489771-37556693 (-)
A/J MGP_AJ_G0032079
 protein coding gene Chr7:36452717-36516332 (-)
AKR/J MGP_AKRJ_G0032012
 protein coding gene Chr7:37357246-37423486 (-)
BALB/cJ MGP_BALBcJ_G0032086
 protein coding gene Chr7:36761059-36828385 (-)
C3H/HeJ MGP_C3HHeJ_G0031803
 protein coding gene Chr7:38244874-38309194 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032563
 protein coding gene Chr7:39321837-39393425 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029596
 protein coding gene Chr7:37165401-37226793 (-)
CAST/EiJ MGP_CASTEiJ_G0031138
 protein coding gene Chr7:29496972-29566545 (-)
CBA/J MGP_CBAJ_G0031771
 protein coding gene Chr7:40551524-40618047 (-)
DBA/2J MGP_DBA2J_G0031923
 protein coding gene Chr7:36287081-36351733 (-)
FVB/NJ MGP_FVBNJ_G0031876
 protein coding gene Chr7:36209389-36274154 (-)
LP/J MGP_LPJ_G0032000
 protein coding gene Chr7:37847102-37910390 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031916
 protein coding gene Chr7:39373208-39441323 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032578
 protein coding gene Chr7:36962630-37032860 (-)
PWK/PhJ MGP_PWKPhJ_G0030860
 protein coding gene Chr7:29670439-29735887 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030695
 protein coding gene Chr7:26521453-26592683 (-)
WSB/EiJ MGP_WSBEiJ_G0031248
 protein coding gene Chr7:37475899-37541088 (-)



Homology
more
  • Human Ortholog
    URI1, URI1 prefoldin like chaperone
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    URI1, URI1 prefoldin like chaperone
  • Synonyms
    C19orf2, NNX3, PPP1R19, RMP, URI
  • Links
    NCBI Gene ID: 8725
    neXtProt AC: NX_O94763
    UniProt: O94763

  • Chr Location
    19q12; chr19:29923644-30016612 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    832
  • Tissues
    68
  • cDNA Data
    19
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030421 Ensembl Gene Model | MGI Sequence Detail 63560 C57BL/6J ±  kb
    transcript ENSMUST00000206581 Ensembl | MGI Sequence Detail 1753 Not Applicable  
    polypeptide ENSMUSP00000145738 Ensembl | MGI Sequence Detail 533 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      Genomic 3
      cDNA 19
      Primer pair 2

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGI:2142349
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 8
      Gene Ontology 5
      Phenotypes 17
    • Earliest
      J:52000 Van Leuven F, et al., Molecular cloning of a gene on chromosome 19q12 coding for a novel intracellular protein: analysis of expression in human and mouse tissues and in human tumor cells, particularly Reed-Sternberg cells in Hodgkin disease. Genomics. 1998 Dec 15;54(3):511-20
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory