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Ndufc2 Gene Detail
Summary
  • Symbol
    Ndufc2
  • Name
    NADH:ubiquinone oxidoreductase subunit C2
  • Synonyms
    14.5b subunit of the NADH-ubiquinone dehydrogenase complex, 1810004I06Rik, 2010300P09Rik, G1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1344370
    NCBI Gene: 68197
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:97049210-97057007 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 53.49 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    421 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1344370
 protein coding gene Chr7:97049210-97057009 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032523
 protein coding gene Chr7:100092306-100101280 (+)
A/J MGP_AJ_G0032497
 protein coding gene Chr7:97610631-97618528 (+)
AKR/J MGP_AKRJ_G0032433
 protein coding gene Chr7:99931041-99940449 (+)
BALB/cJ MGP_BALBcJ_G0032508
 protein coding gene Chr7:97301935-97310584 (+)
C3H/HeJ MGP_C3HHeJ_G0032223
 protein coding gene Chr7:100288265-100296056 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033006
 protein coding gene Chr7:103985606-103994805 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030001
 protein coding gene Chr7:100066349-100074502 (+)
CAST/EiJ MGP_CASTEiJ_G0031550
 protein coding gene Chr7:91801099-91809867 (+)
CBA/J MGP_CBAJ_G0032190
 protein coding gene Chr7:107499819-107509382 (+)
DBA/2J MGP_DBA2J_G0032342
 protein coding gene Chr7:95971316-95980458 (+)
FVB/NJ MGP_FVBNJ_G0032298
 protein coding gene Chr7:95754958-95764718 (+)
LP/J MGP_LPJ_G0032431
 protein coding gene Chr7:101419728-101427500 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032331
 protein coding gene Chr7:109043067-109050964 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033028
 protein coding gene Chr7:99225372-99233157 (+)
PWK/PhJ MGP_PWKPhJ_G0031268
 protein coding gene Chr7:89025463-89039044 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031111
 protein coding gene Chr7:86461508-86469267 (+)
WSB/EiJ MGP_WSBEiJ_G0031667
 protein coding gene Chr7:99862508-99870288 (+)



Homology
more
  • Human Ortholog
    NDUFC2, NADH:ubiquinone oxidoreductase subunit C2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFC2, NADH:ubiquinone oxidoreductase subunit C2
  • Synonyms
    B14.5b, CI-B14.5b, HLC-1, MC1DN36, NADHDH2
  • Links
    NCBI Gene ID: 4718
    neXtProt AC: NX_O95298
    UniProt: O95298

  • Chr Location
    11q14.1; chr11:78068297-78079862 (-)  GRCh38
  • Human Ortholog
    NDUFC2-KCTD14, NDUFC2-KCTD14 readthrough
  • Links
    NCBI Gene ID: 100532726
    neXtProt AC: NX_E9PQ53
    UniProt: E9PQ53

  • Chr Location
    11q14.1; chr11:78015715-78079865 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human NDUFC2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    31 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    815
  • Tissues
    102
  • cDNA Data
    146
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68197 NCBI Gene Model | MGI Sequence Detail 7798 C57BL/6J ±  kb
transcript NM_024220 RefSeq | MGI Sequence Detail 693 C57BL/6  
polypeptide Q9CQ54 UniProt | EBI | MGI Sequence Detail 120 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 146
    cDNA 146

    Microarray probesets 5
Other
Accession IDs
less
MGI:1915447, MGI:1919437, MGI:2144702
References
more
  • Summaries
    All 67
    Developmental Gene Expression 4
    Gene Ontology 11
    Phenotypes 31
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory