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Psmd13 Gene Detail
Summary
  • Symbol
    Psmd13
  • Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
  • Synonyms
    26S proteasome subunit p40.5, S11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1345192
    NCBI Gene: 23997
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140462307-140478555 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.09 cM, cytoband F5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    427 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1345192
 protein coding gene Chr7:140461881-140478556 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033198
 protein coding gene Chr7:146019136-146035868 (+)
A/J MGP_AJ_G0033180
 protein coding gene Chr7:141866055-141882544 (+)
AKR/J MGP_AKRJ_G0033112
 protein coding gene Chr7:145752077-145773277 (+)
BALB/cJ MGP_BALBcJ_G0033181
 protein coding gene Chr7:141593792-141610409 (+)
C3H/HeJ MGP_C3HHeJ_G0032895
 protein coding gene Chr7:145511934-145530242 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033692
 protein coding gene Chr7:151356431-151381644 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030665
 protein coding gene Chr7:143076376-143090985 (+)
CAST/EiJ MGP_CASTEiJ_G0032225
 protein coding gene Chr7:137810992-137827994 (+)
CBA/J MGP_CBAJ_G0032867
 protein coding gene Chr7:156486673-156508446 (+)
DBA/2J MGP_DBA2J_G0033020
 protein coding gene Chr7:139804075-139820003 (+)
FVB/NJ MGP_FVBNJ_G0032972
 protein coding gene Chr7:139714778-139733032 (+)
LP/J MGP_LPJ_G0033114
 protein coding gene Chr7:147518944-147537825 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033005
 protein coding gene Chr7:157154143-157172668 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033712
 protein coding gene Chr7:144739717-144757437 (+)
PWK/PhJ MGP_PWKPhJ_G0031930
 protein coding gene Chr7:133072971-133092072 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031776
 protein coding gene Chr7:131558302-131573514 (+)
WSB/EiJ MGP_WSBEiJ_G0032336
 protein coding gene Chr7:145658414-145677512 (+)



Homology
more
  • Human Ortholog
    PSMD13, proteasome 26S subunit, non-ATPase 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMD13, proteasome 26S subunit, non-ATPase 13
  • Synonyms
    HSPC027, p40.5, Rpn9, S11
  • Links
    NCBI Gene ID: 5719
    neXtProt AC: NX_Q9UNM6
    UniProt: Q9UNM6

  • Chr Location
    11p15.5; chr11:236966-252984 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    729
  • Tissues
    5
  • cDNA Data
    178
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 23997 NCBI Gene Model | MGI Sequence Detail 16249 C57BL/6J ±  kb
transcript NM_011875 RefSeq | MGI Sequence Detail 1563 C57BL/6  
polypeptide Q9WVJ2 UniProt | EBI | MGI Sequence Detail 376 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000002179 26S proteasome non-ATPase regulatory subunit 13
    (term hierarchy)
  • InterPro Domains
    IPR035298 26S Proteasome non-ATPase regulatory subunit 13
    IPR000717 Proteasome component (PCI) domain
    IPR036390 Winged helix DNA-binding domain superfamily
  • GlyGen
    Q9WVJ2 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 178
    cDNA 178

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:54629 Hoffman L, et al., Identification, molecular cloning, and characterization of subunit 11 of the human 26S proteasome. FEBS Lett. 1999 Apr 16;449(1):88-92
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory