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Plaat1 Gene Detail
Summary
  • Symbol
    Plaat1
  • Name
    phospholipase A and acyltransferase 1
  • Synonyms
    2810012B06Rik, A-C1, Hrasls
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351473
    NCBI Gene: 27281
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:29028447-29049283 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 20.01 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    669 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351473
 protein coding gene Chr16:29027883-29049283 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022703
 protein coding gene Chr16:27043885-27064701 (+)
A/J MGP_AJ_G0022666
 protein coding gene Chr16:25804446-25825266 (+)
AKR/J MGP_AKRJ_G0022640
 protein coding gene Chr16:26778755-26799547 (+)
BALB/cJ MGP_BALBcJ_G0022670
 protein coding gene Chr16:25987462-26008269 (+)
C3H/HeJ MGP_C3HHeJ_G0022435
 protein coding gene Chr16:26887823-26908620 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023119
 protein coding gene Chr16:27613424-27634252 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020637
 protein coding gene Chr16:26273475-26294122 (+)
CAST/EiJ MGP_CASTEiJ_G0021963
 protein coding gene Chr16:26960450-26981154 (+)
CBA/J MGP_CBAJ_G0022405
 protein coding gene Chr16:28795438-28816262 (+)
DBA/2J MGP_DBA2J_G0022538
 protein coding gene Chr16:25691915-25712699 (+)
FVB/NJ MGP_FVBNJ_G0022513
 protein coding gene Chr16:25665754-25686547 (+)
LP/J MGP_LPJ_G0022605
 protein coding gene Chr16:26842650-26863434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022532
 protein coding gene Chr16:28387192-28407921 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023131
 protein coding gene Chr16:26730449-26751221 (+)
PWK/PhJ MGP_PWKPhJ_G0021702
 protein coding gene Chr16:25987840-26008760 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021533
 protein coding gene Chr16:26498824-26519672 (+)
WSB/EiJ MGP_WSBEiJ_G0022007
 protein coding gene Chr16:26667814-26692282 (+)



Homology
more
  • Human Ortholog
    PLAAT1, phospholipase A and acyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLAAT1, phospholipase A and acyltransferase 1
  • Synonyms
    A-C1, HRASLS, HRASLS1, H-REV107, HRSL1, HSD28, PLA/AT1, PLAAT-1
  • Links
    NCBI Gene ID: 57110
    neXtProt AC: NX_Q9HDD0
    UniProt: Q9HDD0

  • Chr Location
    3q29; chr3:193240606-193281426 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    24
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022525 Ensembl Gene Model | MGI Sequence Detail 20837 C57BL/6J ±  kb
transcript ENSMUST00000162747 Ensembl | MGI Sequence Detail 854 Not Applicable  
polypeptide ENSMUSP00000123809 Ensembl | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923613, MGI:6285804
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 12
    Phenotypes 4
  • Earliest
    J:58251 Akiyama H, et al., Molecular cloning and biological activity of a novel Ha-Ras suppressor gene predominantly expressed in skeletal muscle, heart, brain, and bone marrow by differential display using clonal mouse EC cells, ATDC5. J Biol Chem. 1999 Nov 5;274(45):32192-7
  • Latest
    J:343807 Rahman SMK, et al., PLAAT1 deficiency alleviates high-fat diet-induced hepatic lipid accumulation in mice. FASEB J. 2023 Jul;37(7):e23032
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory