About   Help   FAQ
Psmd7 Gene Detail
Summary
  • Symbol
    Psmd7
  • Name
    proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
  • Synonyms
    Mov-34, Mov34
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351511
    NCBI Gene: 17463
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:108307013-108315096 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 54.38 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    322 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351511
 protein coding gene Chr8:108307012-108315114 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034103
 protein coding gene Chr8:110053895-110062887 (-)
A/J MGP_AJ_G0034083
 protein coding gene Chr8:105615511-105623614 (-)
AKR/J MGP_AKRJ_G0034009
 protein coding gene Chr8:108696737-108707391 (-)
BALB/cJ MGP_BALBcJ_G0034076
 protein coding gene Chr8:105825653-105833621 (-)
C3H/HeJ MGP_C3HHeJ_G0033788
 protein coding gene Chr8:109427530-109436702 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034596
 protein coding gene Chr8:114033919-114044063 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031538
 protein coding gene Chr8:98711081-98719416 (-)
CAST/EiJ MGP_CASTEiJ_G0033115
 protein coding gene Chr8:108970149-108979937 (-)
CBA/J MGP_CBAJ_G0033761
 protein coding gene Chr8:117742574-117756074 (-)
DBA/2J MGP_DBA2J_G0033916
 protein coding gene Chr8:104947722-104956091 (-)
FVB/NJ MGP_FVBNJ_G0033861
 protein coding gene Chr8:103892460-103900538 (-)
LP/J MGP_LPJ_G0034007
 protein coding gene Chr8:110239870-110249566 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033906
 protein coding gene Chr8:120876570-120884521 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034615
 protein coding gene Chr8:108648084-108660104 (-)
PWK/PhJ MGP_PWKPhJ_G0032817
 protein coding gene Chr8:104374394-104382569 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032656
 protein coding gene Chr8:107364460-107372782 (-)
WSB/EiJ MGP_WSBEiJ_G0033230
 protein coding gene Chr8:109351237-109360428 (-)



Homology
more
  • Human Ortholog
    PSMD7, proteasome 26S subunit, non-ATPase 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMD7, proteasome 26S subunit, non-ATPase 7
  • Synonyms
    MOV34, P40, Rpn8, S12
  • Links
    NCBI Gene ID: 5713
    neXtProt AC: NX_P51665
    UniProt: P51665

  • Chr Location
    16q23.1; chr16:74296814-74306288 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutant mice carrying a proviral insertion at this locus develop normally to the blastocyst stage but die shortly after implantation before reaching the egg cylinder stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    726
  • Tissues
    7
  • cDNA Data
    82
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039067 Ensembl Gene Model | MGI Sequence Detail 8084 C57BL/6J ±  kb
transcript ENSMUST00000044106 Ensembl | MGI Sequence Detail 1581 Not Applicable  
polypeptide ENSMUSP00000041968 Ensembl | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 91
    Genomic 6
    cDNA 84
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-12369, MGD-MRK-12387, MGI:2142756, MGI:97063
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:8921 Soriano P, et al., Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. Genes Dev. 1987 Jun;1(4):366-75
  • Latest
    J:228828 Hamazaki J, et al., Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis. PLoS Genet. 2015 Jul;11(7):e1005401
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory