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Tcl1b2 Gene Detail
Summary
  • Symbol
    Tcl1b2
  • Name
    T cell leukemia/lymphoma 1B, 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351609
    NCBI Gene: 27381
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr12:105113278-105121484 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 55.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351609
 protein coding gene Chr12:105112273-105121484 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020084
 protein coding gene Chr12:106991729-107012751 (+)
A/J MGP_AJ_G0020039
 protein coding gene Chr12:102969102-103010191 (+)
AKR/J MGP_AKRJ_G0020015
 protein coding gene Chr12:105915341-105925181 (+)
BALB/cJ MGP_BALBcJ_G0020024
 protein coding gene Chr12:103355111-103471295 (+)
C3H/HeJ MGP_C3HHeJ_G0019827
 protein coding gene Chr12:106388002-106437524 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020470
 protein coding gene Chr12:110284019-110330914 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018085
 protein coding gene Chr12:99658000-99665435 (+)
CAST/EiJ MGP_CASTEiJ_G0019371
 protein coding gene Chr12:101234089-101240159 (+)
CBA/J MGP_CBAJ_G0019794
 protein coding gene Chr12:114606909-114613793 (+)
DBA/2J MGP_DBA2J_G0019912
 protein coding gene Chr12:102481137-102508354 (+)
FVB/NJ MGP_FVBNJ_G0019896
 protein coding gene Chr12:101263951-101367230 (+)
LP/J MGP_LPJ_G0019986
 protein coding gene Chr12:106871009-106938487 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019934
 protein coding gene Chr12:118016524-118094089 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020499
 protein coding gene Chr12:105305238-105387532 (+)
PWK/PhJ MGP_PWKPhJ_G0019131
 protein coding gene Chr12:97010825-97066946 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0019428
 protein coding gene Chr12:106291209-106359274 (+)



Homology
more
  • Human Ortholog
    TCL1B, TCL1 family AKT coactivator B
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCL1B, TCL1 family AKT coactivator B
  • Synonyms
    SYN-1, TML1
  • Links
    NCBI Gene ID: 9623
    neXtProt AC: NX_O95988
    UniProt: O95988

  • Chr Location
    14q32.13; chr14:95686426-95692628 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Tcl1b2
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 27381 NCBI Gene Model | MGI Sequence Detail 8207 C57BL/6J ±  kb
transcript NR_155261 RefSeq | MGI Sequence Detail 1095 C57BL/6  
polypeptide P56841 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    Genomic 1
    cDNA 10

    Microarray probesets 1
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:58922 Hallas C, et al., Genomic analysis of human and mouse TCL1 loci reveals a complex of tightly clustered genes. Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14418-23
  • Latest
    J:256712 Yu C, et al., Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. Cell Res. 2016 Mar;26(3):275-87
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory