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Abcf3 Gene Detail
Summary
  • Symbol
    Abcf3
  • Name
    ATP-binding cassette, sub-family F member 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351656
    NCBI Gene: 27406
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:20367327-20380129 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 12.46 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    314 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351656
 protein coding gene Chr16:20367309-20380357 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022645
 protein coding gene Chr16:17887081-17899907 (+)
A/J MGP_AJ_G0022607
 protein coding gene Chr16:17024931-17039160 (+)
AKR/J MGP_AKRJ_G0022582
 protein coding gene Chr16:17676503-17689296 (+)
BALB/cJ MGP_BALBcJ_G0022611
 protein coding gene Chr16:17187055-17200263 (+)
C3H/HeJ MGP_C3HHeJ_G0022376
 protein coding gene Chr16:17837779-17851475 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023062
 protein coding gene Chr16:18236685-18249491 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020579
 protein coding gene Chr16:17714975-17728382 (+)
CAST/EiJ MGP_CASTEiJ_G0021906
 protein coding gene Chr16:17810362-17826869 (+)
CBA/J MGP_CBAJ_G0022348
 protein coding gene Chr16:18980115-18992913 (+)
DBA/2J MGP_DBA2J_G0022480
 protein coding gene Chr16:16953479-16966524 (+)
FVB/NJ MGP_FVBNJ_G0022455
 protein coding gene Chr16:16983832-16996624 (+)
LP/J MGP_LPJ_G0022547
 protein coding gene Chr16:17618255-17631426 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022475
 protein coding gene Chr16:18666431-18680400 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023073
 protein coding gene Chr16:17632852-17646679 (+)
PWK/PhJ MGP_PWKPhJ_G0021647
 protein coding gene Chr16:17216612-17229416 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021476
 protein coding gene Chr16:17438205-17452259 (+)
WSB/EiJ MGP_WSBEiJ_G0021950
 protein coding gene Chr16:17623631-17636421 (+)



Homology
more
  • Human Ortholog
    ABCF3, ATP binding cassette subfamily F member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABCF3, ATP binding cassette subfamily F member 3
  • Synonyms
    EST201864
  • Links
    NCBI Gene ID: 55324
    neXtProt AC: NX_Q9NUQ8
    UniProt: Q9NUQ8

  • Chr Location
    3q27.1; chr3:184186095-184194012 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    782
  • Tissues
    6
  • cDNA Data
    124
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000003234 Ensembl Gene Model | MGI Sequence Detail 12803 C57BL/6J ±  kb
transcript ENSMUST00000003319 Ensembl | MGI Sequence Detail 3090 Not Applicable  
polypeptide ENSMUSP00000003319 Ensembl | MGI Sequence Detail 709 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000029257 ATP-binding cassette sub-family F member 3
    (term hierarchy)
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR032781 ABC-transporter extension domain
    IPR003439 ABC transporter-like, ATP-binding domain
    IPR017871 ABC transporter-like, conserved site
    IPR050611 ATP-binding cassette sub-family F member, EF3 subfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
  • GlyGen
    Q8K268 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 124
    cDNA 124

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146416, MGI:2146544, MGI:2146682
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60841 Schriml LM, et al., Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus. Genomics. 2000 Feb 15;64(1):24-31
  • Latest
    J:282785 Peterson E, et al., Biochemical characterization of the mouse ABCF3 protein, a partner of the flavivirus-resistance protein OAS1B. J Biol Chem. 2019 Oct 11;294(41):14937-14952
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory