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Timm8b Gene Detail
Summary
  • Symbol
    Timm8b
  • Name
    translocase of inner mitochondrial membrane 8B
  • Synonyms
    Tim8b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353424
    NCBI Gene: 30057
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:50515227-50516620 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 27.75 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353424
 protein coding gene Chr9:50515210-50516620 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034782
 protein coding gene Chr9:49503197-49504616 (+)
A/J MGP_AJ_G0034763
 protein coding gene Chr9:47987547-47988966 (+)
AKR/J MGP_AKRJ_G0034691
 protein coding gene Chr9:48999209-49000628 (+)
BALB/cJ MGP_BALBcJ_G0034755
 protein coding gene Chr9:47715218-47716637 (+)
C3H/HeJ MGP_C3HHeJ_G0034465
 protein coding gene Chr9:49486652-49488071 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035275
 protein coding gene Chr9:50879853-50881272 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032188
 protein coding gene Chr9:47455878-47457235 (+)
CAST/EiJ MGP_CASTEiJ_G0033787
 protein coding gene Chr9:49435258-49436677 (+)
CBA/J MGP_CBAJ_G0034437
 protein coding gene Chr9:52693097-52694516 (+)
DBA/2J MGP_DBA2J_G0034596
 protein coding gene Chr9:47851817-47853236 (+)
FVB/NJ MGP_FVBNJ_G0034537
 protein coding gene Chr9:47068782-47070206 (+)
LP/J MGP_LPJ_G0034677
 protein coding gene Chr9:49863392-49864811 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034580
 protein coding gene Chr9:54289398-54290817 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035296
 protein coding gene Chr9:48977235-48978654 (+)
PWK/PhJ MGP_PWKPhJ_G0033492
 protein coding gene Chr9:47828648-47830067 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033327
 protein coding gene Chr9:49288453-49289872 (+)
WSB/EiJ MGP_WSBEiJ_G0033900
 protein coding gene Chr9:48983867-48985286 (+)



Homology
more
  • Human Ortholog
    TIMM8B, translocase of inner mitochondrial membrane 8 homolog B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TIMM8B, translocase of inner mitochondrial membrane 8 homolog B
  • Synonyms
    DDP2, TIM8B
  • Links
    NCBI Gene ID: 26521
    neXtProt AC: NX_Q9Y5J9
    UniProt: Q9Y5J9

  • Chr Location
    11q23.1; chr11:112084800-112086798 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    860
  • Tissues
    40
  • cDNA Data
    11
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 30057 NCBI Gene Model | MGI Sequence Detail 1394 C57BL/6J ±  kb
transcript NM_013897 RefSeq | MGI Sequence Detail 501 C57BL/6  
polypeptide P62077 UniProt | EBI | MGI Sequence Detail 83 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:58613 Jin H, et al., The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins. Genomics. 1999 Nov 1;61(3):259-67
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory