Sles1 QTL Detail

Summary

• Symbol
  Sles1
• Name
  systemic lupus erythmatosus suppressor 1

• Feature Type
  QTL
• IDs
  MGI:1353464
  NCBI Gene: 109491

Location &
Maps

• Sequence Map
  Chr17:34219890-35175937 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 18.31 cM (cM position of peak correlated region/marker)
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 2 alleles in 1 genetic background
  2 phenotypes from multigenic genotypes
  4 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

Sequences &
Gene Models

• NCBI Gene
  109491

References

• Summaries
  All 5

  Phenotypes 4
• Earliest
  J:111094 Miyazaki T, Two distinct steps during thymocyte maturation from CD4-CD8- to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient background. J Exp Med. 1997 Sep 15;186(6):877-85
• Latest
  J:111064 Subramanian S, et al., A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9970-5