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Snai3 Gene Detail
Summary
  • Symbol
    Snai3
  • Name
    snail family zinc finger 3
  • Synonyms
    Smuc, Snail-related gene from muscle cells, Zfp293
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353563
    NCBI Gene: 30927
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:123180947-123187472 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 71.07 cM, cytoband E1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    288 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353563
 protein coding gene Chr8:123180943-123187546 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034226
 protein coding gene Chr8:125992519-125999006 (-)
A/J MGP_AJ_G0034206
 protein coding gene Chr8:120779167-120785670 (-)
AKR/J MGP_AKRJ_G0034133
 protein coding gene Chr8:124297847-124304350 (-)
BALB/cJ MGP_BALBcJ_G0034200
 protein coding gene Chr8:120980299-120986802 (-)
C3H/HeJ MGP_C3HHeJ_G0033911
 protein coding gene Chr8:124995698-125002201 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034720
 protein coding gene Chr8:130196246-130202732 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031662
 protein coding gene Chr8:113614465-113621155 (-)
CAST/EiJ MGP_CASTEiJ_G0033238
 protein coding gene Chr8:125076336-125082814 (-)
CBA/J MGP_CBAJ_G0033884
 protein coding gene Chr8:134982764-134989250 (-)
DBA/2J MGP_DBA2J_G0034040
 protein coding gene Chr8:119970006-119976492 (-)
FVB/NJ MGP_FVBNJ_G0033983
 protein coding gene Chr8:119112978-119120048 (-)
LP/J MGP_LPJ_G0034129
 protein coding gene Chr8:126120484-126126971 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034030
 protein coding gene Chr8:137162743-137169249 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034738
 protein coding gene Chr8:124480495-124486981 (-)
PWK/PhJ MGP_PWKPhJ_G0032940
 protein coding gene Chr8:119790067-119796586 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032780
 protein coding gene Chr8:123206298-123212816 (-)
WSB/EiJ MGP_WSBEiJ_G0033354
 protein coding gene Chr8:125235998-125242503 (-)



Homology
more
  • Human Ortholog
    SNAI3, snail family transcriptional repressor 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNAI3, snail family transcriptional repressor 3
  • Synonyms
    SMUC, SNAIL3, Zfp293, ZNF293
  • Links
    NCBI Gene ID: 333929
    neXtProt AC: NX_Q3KNW1
    UniProt: Q3KNW1

  • Chr Location
    16q24.2; chr16:88677688-88686507 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 5 alleles in 4 genetic backgrounds
    17 phenotypes from multigenic genotypes
    9 phenotype references
Mice homozygous for a knock-out allele exhibit no abnormal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1030
  • Tissues
    248
  • cDNA Data
    17
  • Literature Summary
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006587 Ensembl Gene Model | MGI Sequence Detail 6526 C57BL/6J ±  kb
transcript ENSMUST00000006762 Ensembl | MGI Sequence Detail 1628 Not Applicable  
polypeptide ENSMUSP00000006762 Ensembl | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    Genomic 1
    cDNA 17

    Microarray probesets 5
Other
Accession IDs
less
MGI:2142599
References
more
  • Summaries
    All 49
    Developmental Gene Expression 13
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:59877 Kataoka H, et al., A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs. Nucleic Acids Res. 2000 Jan 15;28(2):626-33
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory